ConspectusChimeric antigen receptor (CAR) T-cell therapy has changed the landscape of cancer treatments, utilizing modified ex vivo autologous T cells to treat relapsed or refractory B-cell leukemia and lymphoma. However, the impact of wider therapy has been limited, in part, the production process is complicated, lengthy, and expensive. Thus, as a T-cell therapy CAR more developed to treat other cancers, continuous innovation in manufacturing cell will be crucial to their successful clinical implementation.

This account, we describe our research efforts using biomaterials to raise three fundamental steps in T-cell manufacturing CAR: (1) isolation, (2) activation, and (3) genetic modification.Recognizing T cell isolation reagent clinically and supply costs a high obstacle, we developed a synthetic DNA aptamer and complementary reversal agent technology that CD8 + T cells isolated label-free with high purity and yield of mononuclear cells of peripheral blood. Spirit, CAR T cells are made of both antibody and T cell-isolated aptamer comparable in therapeutic potential.

Invention and design of other T-cell specific aptamers and corresponding reversal reagents can fully realize the potential of this approach, enabling inexpensive isolation of different T cell populations in a single insulating step.Current some material ex vivo T-cell activation does not accurately mimic the in situ activation of cells T by antigen presenting cells (APC). They are not the same cause expansion of CD4 + and CD8 + T cells, so it requires a separate production of CD4 + and CD8 + CAR T cells for therapeutic infusion calls for balanced composition.

To address this shortcoming, we designed a panel of cell-templated silica microparticles with a biodegradable supported lipid bilayers that display ligand stimulation of T-cell activation. high fluidity of the membrane, elongated shape, and rugged topography of the surface, all of the properties of endogenous APC, which was found to be a favorable parameter for activation, promote unbiased and efficient CD4 / CD8 T-cell expansion while not severe distinguish cells.

Viral and electroporation-based delivery system gene has many weaknesses. viral vectors are expensive and limited the size of the cargo, while the highly cytotoxic electroporation. Thus, low-cost platform nonviral that transfect T cells with low cytotoxicity and high efficiency required for CAR gene delivery. Our group thus synthesized cationic polymer panels with different architectures and evaluated their abilities T cell transfection.

We identified a comb-shaped polymer formulations were transfected primary T cells with low cytotoxicity, although it was a low transfection efficiency compared to conventional methods. Analysis of intracellular and extracellular barriers to transfection reveal polyplexes low absorption and high endosomal pH in T cells, offensive biological properties and polymers that can further innovation improved.These represent only a few recent developments in the field of biomaterials to address the needs of CAR T cell production. Together, these technologies and their future progress would pave the way for the manufacture of T-cell CAR economical and easy.

Breast cancer and normal tissue array with stage and grade info
BR8012	TissueArray	each	EUR 306
Description: Breast cancer and normal tissue array with stage and grade info, 40 cases/80 cores, replaced by BR8014

Human Cancer PrimaCell4: Breast Tumor Cells Growth Medium
9-46027	CHI Scientific	5 x 100 ml	Ask for price

Breast Cancer-Associated Antigen BRCAA1 (BRCAA1) Antibody
20-abx148333	Abbexa	EUR 510.00 EUR 410.40	100 ug 50 ug

Human Cancer Tissue Preparation Buffer 4: Breast Tumor Cells
9-80027	CHI Scientific	1 x 100 ml	Ask for price

BSA (Standard Grade)
30-AB70	Fitzgerald	1 kg	EUR 1078.8
Description: Standard Grade Bovine Serum Albumin (99% pure)

Cancer Antigen 15-3 MUC 1 Antigen (Human Milk)
VAng-Cr3871-10kU	Creative Biolabs	10 kU	EUR 505.2
Description: Cancer Antigen 15-3 MUC 1 Antigen, Host/Source: Human Milk. The purity is detected by salt extraction and delipidization following high speed centrifugation. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

Cancer Antigen 15-3 (CA15-3) (human) ELISA Kit
K4804-100	Biovision	100 assays	EUR 1000.8
Description: Sensitive, Colorimetric Assay

Breast Cancer and 8 types of tumor (middle advanced stage)tissue array
BR20838a	TissueArray	each	EUR 474
Description: Breast Cancer and 8 types of tumor (middle advanced stage)tissue array, including pathology grade, TNM/stage with IHC Her-2 results, 118 cases/208 cores (core size 1.5mm), replacing BR20838

Breast cancer
BR1008b	TissueArray	each	EUR 306
Description: Breast cancer, lymph node metastatic carcinoma and adjacent normal tissue array, including pathology grade, TNM, clinical stage, and ER/PR/Her2 result, 100 cases/100 cores, replacing BR1008a

Breast cancer
BR724	TissueArray	each	EUR 270
Description: Breast cancer, adjacent and adjacent normal tissue array, 66 cases/72 cores

Breast cancer
BR725	TissueArray	each	EUR 270
Description: Breast cancer, adjacent and adjacent normal tissue array, 68 cases/72 cores

Breast tumor tissue array (15 of 25)
BR20821	TissueArray	each	EUR 474
Description: Breast tumor tissue array (15 of 25), including TNM, clinical stage, pathology grade and IHC markers (ER, PR, Her-2) results,104 cases/208 cores

Cancer Antigen 15-3 MUC 1 Antigen (Human Ascites Fluid)
VAng-Cr3872-10kU	Creative Biolabs	10 kU	EUR 1363.2
Description: Cancer Antigen 15-3 MUC 1 Antigen, Host/Source: Human Ascites Fluid.

Breast Tumor Tissue Array - 16 cases of breast cancer, each in duplicates, paired with adjacent normal tissues
Z7020007	Biochain	5 slides	EUR 1657.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Breast cancer with cancer adjacent breast tissue array
BC081116e	TissueArray	each	EUR 306
Description: Breast cancer with cancer adjacent breast tissue array, including invasive carcinoma of no special type, breast carcinoma with apocrine differentiation and AT tissue,pat hology grade, IHC (ER/PR/Her-2/Ki67) info, TNM/Stage (AJCC 7th edition), 107 cases/110 cores (core size 1.5mm), replacing BC081116d

CancerSeq™ Paraffin Tissue Tumor Block: Breast
T2235086-SB	Biochain	1 Block	EUR 4014

CancerSeq™ Paraffin Tissue Tumor Slides: Breast
T2235086-ST	Biochain	5 Slides	EUR 572

Breast cancer TMA
BR602	TissueArray	each	EUR 270
Description: Breast cancer TMA, 3 samples have matched cancer adjacent tissue samples, including pathology grade, TNM and clinical stage (reference AJCC 8th version), 57 cases/60 cores (Core Size 1.5mm), recent tear collections

Breast cancer with matched cancer adjacent breast tissue array
BR804b	TissueArray	each	EUR 306
Description: Breast cancer with matched cancer adjacent breast tissue array, including pathology grade, TNM, clinical stage and IHC markers (ER, PR, Her-2 and Ki67), 40 cases/80 cores, replacing BR804a

Breast cancer with breast tissue array
BC08118a	TissueArray	each	EUR 258
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical stage, 100 cases/100 cores (core size 1.0mm), replacing BC08118

Breast cancer with breast tissue array
BR2085d	TissueArray	each	EUR 546
Description: Breast cancer with breast tissue array, including pathology grad, TNM and clinical stage, 188 cases/208 cores, replacing BR2085c

Breast cancer with breast tissue array
BR246d	TissueArray	each	EUR 66
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical stage (reference AJCC 7th version), 12 cases/24 cores, replacing BR246c

Breast cancer with breast tissue array
BR482	TissueArray	each	EUR 198
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical stage, 24 cases/48 cores

Breast cancer with breast tissue array
BR720	TissueArray	each	EUR 270
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical satge (reference AJCC 7th version), 72 cases/72 cores

Breast cancer with breast tissue array
T087d	TissueArray	each	EUR 66
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T087c

Breast cancer with breast tissue array
T088d	TissueArray	each	EUR 66
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T088c

Proteinase K, Recombinant, Standard Grade
9250-100	Biovision	each	EUR 124.8

Proteinase K, Recombinant, Standard Grade
9250-10G	Biovision	each	EUR 4627.2

Proteinase K, Recombinant, Standard Grade
9250-1G	Biovision	each	EUR 548.4

Proteinase K, Recombinant, Standard Grade
9250-500	Biovision	each	EUR 314.4

Proteinase K, Recombinant, Standard Grade
9251-100	Biovision	each	EUR 1266

Proteinase K, Recombinant, Standard Grade
9251-25	Biovision	each	EUR 352.8

Proteinase K, Recombinant, Standard Grade
9251-5	Biovision	each	EUR 144

Breast Tumor Tissue Array - duplicated 70 cases covering all the common types of breast cancer and 5 cases of normal and
Z7020004	Biochain	5 slides	EUR 1293

Breast Tumor Tissue Array - Duplicated 70 cases covering all the common types of breast cancer and 5 cases of normal and
Z7020005	Biochain	5 slides	EUR 1293

Breast Tumor Tissue Array - Duplicated 36 cases covering all the common types of breast cancer and 12 cases of normal an
Z7020008	Biochain	5 slides	EUR 1657.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Breast Tumor Tissue Array - Duplicated 36 cases covering all the common types of breast cancer and 12 cases of normal an
Z7020009	Biochain	5 slides	EUR 1657.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Breast Cancer Exosome
P141-BR	101Bio	-	Ask for price

Human Cancer PrimaCell4: Breast Tumor Cells Growth Supplements with Serum (for 500 ml medium)
9-47027	CHI Scientific	1 Set	Ask for price

CA 15-3, Human Breast Adenocarcinoma
P1435-1	Biovision	each	EUR 130.8

CA 15-3, Human Breast Adenocarcinoma
P1435-5	Biovision	each	EUR 288

CancerSeq™ Plus Paraffin Tissue Tumor Sections: Breast
T2235086-SC	Biochain	5 curls	EUR 779

Breast cancer tissue array with cancer adjacent breast tissue as control
BR208a	TissueArray	each	EUR 474
Description: Breast cancer tissue array with cancer adjacent breast tissue as control, including TNM, clinical stage and pathology grade, 69 cases/ 207 cores.

Breast cancer (including one case of male breast cancer) with adjacent normal breast tissue array
BC081120g	TissueArray	each	EUR 306
Description: Breast cancer (including one case of male breast cancer) with adjacent normal breast tissue array, including pathology grade, TNM and clinical stage (AJCC 7th edition) with IHC results ER/PR/Her2/Ki67,110 cases/110 cores (core size 1.0 mm), replacing BC081120f

Ovarian Cancer Antigen (CA 125)
CA1251-N-10	Alpha Diagnostics	10 KU	EUR 634.8

Breast cancer with matched breast tissue array
BR251e	TissueArray	each	EUR 60
Description: Breast cancer with matched breast tissue array, including pathology grade, IHC info (ER,PR,Her-2,Ki67),TNM\Stage, 6 cases/24 cores (core size 1.5mm), replacing BR251d

Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody
20-abx171475	Abbexa	EUR 1028.40 EUR 526.80	1 mg 200 ug

Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody
20-abx324781	Abbexa	EUR 376.80 EUR 292.80	100 ug 50 ug

Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody
20-abx129227	Abbexa	EUR 510.00 EUR 159.60 EUR 1446.00 EUR 693.60 EUR 393.60	100 ug 10 ug 1 mg 200 ug 50 ug

Breast Cancer Exosome RNA
P241-BR	101Bio	-	Ask for price

Multiple breast cancer with breast tissue array
BR087e	TissueArray	each	EUR 48
Description: Multiple breast cancer with breast tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing BR087d

Standard grade heat shock BSA powder, pH 7
BAH62-0050	Equitech	50gm	EUR 308.88

Standard grade heat shock BSA powder, pH 7
BAH62-0100	Equitech	100gm	EUR 388.44

Standard grade heat shock BSA powder, pH 7
BAH62-0500	Equitech	500gm	EUR 511.68

Standard grade heat shock BSA powder, pH 7
BAH62-1000	Equitech	1KG	Ask for price

Standard grade heat shock BSA powder, pH 7
BAH62-10000	Equitech	10KG	Ask for price

Standard grade heat shock BSA powder, pH 5.2
BAH63-0050	Equitech	50gm	EUR 308.88

Standard grade heat shock BSA powder, pH 5.2
BAH63-0100	Equitech	100gm	EUR 388.44

Standard grade heat shock BSA powder, pH 5.2
BAH63-0500	Equitech	500gm	EUR 511.68

Standard grade heat shock BSA powder, pH 5.2
BAH63-1000	Equitech	1KG	Ask for price

Standard grade heat shock BSA powder, pH 5.2
BAH63-10000	Equitech	10KG	Ask for price

Breast cancer tissue array
BR042b	TissueArray	each	EUR 78
Description: Breast cancer tissue array, including TNM and pathology grade, 4 cases/4 cores, replacing BR042a

Breast cancer tissue array
BR1006a	TissueArray	each	EUR 306
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, 50 cases/100 cores (core size 1.0mm), replacing BR1006

Breast cancer tissue array
BR1141a	TissueArray	each	EUR 354
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, IHC marker (ER, PR, HER2 and Ki-67), 114 cases/114 cores, replacing BR1141

Breast cancer tissue array
BR1401	TissueArray	each	EUR 414
Description: Breast cancer tissue array, including TNM and pathology grade, IHC markers ER/PR/Her-2 results, 140 cases/140 cores (core size 1.0mm)

Breast cancer tissue array
BR1503f	TissueArray	each	EUR 306
Description: Breast cancer tissue array, including TNM and pathology grade, with IHC results of Her-2\ER\PR\Ki67, 75 cases/ 150 cores, replacing BR1503e

Breast cancer tissue array
BR1505e	TissueArray	each	EUR 306
Description: Breast cancer tissue array, including pathology grade, TNM, clinical stage, and IHC(HER2/ER/PR/Ki67), 75 cases/150 cores, replacing BR1505d

Breast cancer tissue array
BR2161	TissueArray	each	EUR 546
Description: Breast cancer tissue array, including TNM and pathology grade, 216 cases/216 cores

Breast cancer tissue array
BR247a	TissueArray	each	EUR 234
Description: Breast cancer tissue array, with normal tissue, including TNM and pathology grade, IHC marker (HER2), 24 cases/48 cores replacing BR247

Breast cancer tissue array
BR488	TissueArray	each	EUR 306
Description: Breast cancer tissue array, including pathology grade, TNM, clinical stage (AJCC 7th edition), and IHC marker(ER,PR,Her-2), 48 cases/48 cores

Breast cancer tissue array
BR501	TissueArray	each	EUR 270
Description: Breast cancer tissue array, including TNM and pathology grade, 50 cases/ 50 cores (core size 1.5mm)

Breast cancer tissue array
BR8015a	TissueArray	each	EUR 306
Description: Breast cancer tissue array, with adjacent normal tissue and normal tissue, including TNM and pathology grade, 80 cases/80 cores, replacing BC08014

Breast cancer tissue array
BR964	TissueArray	each	EUR 222
Description: Breast cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/96 cores

Breast cancer tissue array
T089c	TissueArray	each	EUR 48
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores(1.5mm), replacing T089b

Microplate cell grade 96well ps standard
781965	Scientific Laboratory Supplies	PK50	EUR 410.4

Recombinant Breast Cancer Anti-Estrogen Resistance 3 (BCAR3)
4-RPG768Hu01	Cloud-Clone	EUR 601.69 EUR 284.40 EUR 1926.34 EUR 722.11 EUR 1324.22 EUR 477.60 EUR 4635.84	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Breast Cancer Anti-Estrogen Resistance 3 expressed in: E.coli

Cancer of the breast, 75 cases (1.1mm), set 3
BRC1503	Pantomics	1	EUR 300
Description: Breast cancer tissue array, set 3, non-overlapping with BRC1501, BRC1502, BRC1504 to BRC15011,150 cores from normal/benign (5 cases) and cancer (70 cases) tissues in duplicates with grading, TNM staging data, AR, ER, PR, HER2, P53, EGFR, Ki67 IHC data.

Cancer Antigen CA-125 Antigen (Human Fluids)
VAng-Wyb8639-inquire	Creative Biolabs	inquire	Ask for price
Description: CA-125, Calibrator Grade, cancer antigen from Human Fluids, 53.26 KU/mL.

Advanced stage breast cancer and normal breast tissue array
BR1191	TissueArray	each	EUR 306
Description: Advanced stage breast cancer and normal breast tissue array, including pathology grade, TNM and clinical stage (AJCC 8.0), ER\PR\HER-2\Ki-67 marker, 119 cases/119 cores, (1.5mm)

Breast normal tissue with breast cancer tissue array
BRN801c	TissueArray	each	EUR 270
Description: Breast normal tissue with breast cancer tissue array, including pathology grade, TNM and clinical stage, 80 cases/80 cores, replacing BRN801b

Cancer Antigen CA 19-9 Antibody
abx023798-1mg	Abbexa	1 mg	EUR 1053.6

Breast cancer with adjacent normal breast tissue array
BR1921c	TissueArray	each	EUR 546
Description: Breast cancer with adjacent normal breast tissue array, including pathology grade, TNM, clinical stage and IHC marker (ER, PR and Her-2), 189 cases/192 cores, replacing BR1921b

Breast cancer with adjacent normal breast tissue array
BR803c	TissueArray	each	EUR 258
Description: Breast cancer with adjacent normal breast tissue array, including pathology grade, TNM and clinical stage, 80 cases/80 cores, replacing BR803b

Breast cancer with adjacent normal breast tissue array
BR901a	TissueArray	each	EUR 270
Description: Breast cancer with adjacent normal breast tissue array, including pathology grade, TNM and clinical stage, 45 cases/90 cores, replacing BR901

Breast Cancer Anti-Estrogen Resistance 1
PR27245	Neuromics	2 ug	EUR 229.2

Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Protein
20-abx168253	Abbexa	EUR 844.80 EUR 343.20 EUR 2598.00 EUR 994.80 EUR 594.00	100 ug 10 ug 1 mg 200 ug 50 ug

Breast Cancer-Associated Gene 3 Protein (BCA3) Antibody
20-abx133658	Abbexa	EUR 360.00 EUR 526.80 EUR 226.80	100 ul 200 ul 30 ul

Breast Cancer-Associated Gene 3 Protein (BCA3) Antibody
abx025588-400ul	Abbexa	400 ul	EUR 627.6

Breast Cancer-Associated Gene 3 Protein (BCA3) Antibody
abx025588-80l	Abbexa	80 µl	EUR 343.2

Breast Cancer-Associated Gene 3 Protein (BCA3) Antibody
20-abx013807	Abbexa	EUR 376.80 EUR 117.60 EUR 477.60 EUR 594.00	100 ug 10 ug 200 ug 300 µg

Breast Cancer Anti-Estrogen Resistance Protein 3 (BCAR3) Antibody
20-abx134976	Abbexa	EUR 427.20 EUR 644.40 EUR 260.40	100 ul 200 ul 30 ul

Breast Cancer Anti-Estrogen Resistance Protein 3 (BCAR3) Antibody
abx218562-100ug	Abbexa	100 ug	EUR 526.8

Breast Cancer Anti-Estrogen Resistance Protein 3 (BCAR3) Antibody
abx432398-200ul	Abbexa	200 ul	EUR 460.8

Breast Cancer Anti-Estrogen Resistance Protein 3 (BCAR3) Antibody
abx010337-100ug	Abbexa	100 ug	EUR 526.8

Breast cancer test tissue array
T086e	TissueArray	each	EUR 66
Description: Breast cancer test tissue array, including TNM, clinical stage and pathology grade, 12 cases/24 cores, replacing T086d

Cancer Antigen CA-125 Antigen (Human Adenocarcinoma)
VAng-Wyb8642-inquire	Creative Biolabs	inquire	Ask for price
Description: CA-125, Calibrator Grade, Cancer antigen from Human Adenocarcinoma, 500 kIU / mL.

Late stage breast cancer tissue array
BR1922	TissueArray	each	EUR 546
Description: Late stage breast cancer tissue array, including TNM, clinical stage and pathology grade, 96 cases/192 cores

Cancer of the breast, 102 cases (1.5mm)
BRC1021	Pantomics	1	EUR 300
Description: Breast cancer tissue array, 102 cases of normal/benign (5 cases) and cancer (97 cases) tissues, with grading, TNM staging, and AR, ER, PR, HER2, P53, EGFR, Ki67 IHC data.

Cancer of the breast, 228 cases (1.1mm)
BRC2281	Pantomics	1	EUR 552
Description: Breast cancer tissue array containing 8 cases of normal/benign conditions and 220 cases of cancers with grading, TNM staging, and AR, ER, PR, HER2, P53, EGFR, Ki67 IHC data.

Bovine Serum Albumin ? Heat Shock, Standard Grade, pH 7.0
7915-100	Biovision	each	EUR 705.6

Bovine Serum Albumin ? Heat Shock, Standard Grade, pH 7.0
7915-25	Biovision	each	EUR 274.8

Bovine Serum Albumin ? Heat Shock, Standard Grade, pH 7.0
7915-5	Biovision	each	EUR 144

Bovine Serum Albumin ? Heat Shock, Standard Grade, pH 5.2
7916-100	Biovision	each	EUR 705.6

Bovine Serum Albumin ? Heat Shock, Standard Grade, pH 5.2
7916-25	Biovision	each	EUR 274.8

Bovine Serum Albumin ? Heat Shock, Standard Grade, pH 5.2
7916-5	Biovision	each	EUR 144

Vitamin A Reference Standard (USP grade powder)
51R-U716002	Fitzgerald	10 pack	EUR 619.2
Description: Vitamin A Reference Standard (USP grade powder) chemical reference substance

Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) CLIA Kit
20-abx495288	Abbexa	EUR 9567.60 EUR 5095.20 EUR 1177.20	10 × 96 tests 5 × 96 tests 96 tests

Breast cancer tissue array (Her-2: 3+/2+/1+/0)
BR082e	TissueArray	each	EUR 78
Description: Breast cancer tissue array (Her-2: 3+/2+/1+/0), including pathology grade, TNM, clinical stage and IHC marker (ER, PR, Her-2 and Ki67), 4 cases/8 cores, replaced by BR082f

Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) ELISA Kit
20-abx150793	Abbexa	EUR 8853.60 EUR 4719.60 EUR 1093.20	10 × 96 tests 5 × 96 tests 96 tests

Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) ELISA Kit
SEG768Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 5677.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) in serum, plasma, tissue homogenates and other biological fluids.

Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) ELISA Kit
SEG768Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 572.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) in serum, plasma, tissue homogenates and other biological fluids.

Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) ELISA Kit
SEG768Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 766.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) in serum, plasma, tissue homogenates and other biological fluids.

Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) ELISA Kit
SEG768Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 3090.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) in serum, plasma, tissue homogenates and other biological fluids.

Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) ELISA Kit
4-SEG768Hu	Cloud-Clone	EUR 5738.40 EUR 3031.20 EUR 768.00	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) in samples from Serum, plasma, tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Breast disease spectrum (breast cancer progression) tissue array
BR2082c	TissueArray	each	EUR 546
Description: Breast disease spectrum (breast cancer progression) tissue array, including pathology grade, TNM and clinical stage, IHC marker (ER, PR, HER2 and Ki-67), 186 cases/192 cores, replacing BR2082b

Breast cancer with matched or unmatched breast tissue array
BR802c	TissueArray	each	EUR 270
Description: Breast cancer with matched or unmatched breast tissue array, including pathology grade, TNM and clinical stage, 53 cases/80 cores, replacing BR802b

Human Serum AB off clot Standard Grade Heat Inactivated
S101BHIEU	Scientific Laboratory Supplies	100ML	EUR 449.16

Breast cancer tissue array with adjacent normal breast tissue
BR8011a	TissueArray	each	EUR 306
Description: Breast cancer tissue array with adjacent normal breast tissue, including TNM, clinical stage, pathology grade and DCIS, 80 cases/80 cores, replacing BR8011

Breast Cancer Metastasis Suppressor 1
PR27265	Neuromics	2 ug	EUR 229.2

Cancer of the breast, 49 cases (2mm)
BRC491	Pantomics	1	EUR 228
Description: Breast cancer tissue array, non-overlapping with BRC711, 49 cases of normal/benign and cancer tissues with grading, TNM staging, and AR, ER, PR, HER2, P53, EGFR, Ki67 IHC data.

Cancer of the breast, 71 cases (1.1mm)
BRC711	Pantomics	1	EUR 228
Description: Breast cancer tissue array, non-overlapping with BRC491, 71 cases of normal/benign and cancer tissues with grading, TNM staging data, AR, ER, PR, HER2, P53, EGFR, Ki67 IHC data.

Breast Cancer Anti-Estrogen Resistance 1 Protein
20-abx262743	Abbexa	EUR 393.60 EUR 7676.40 EUR 276.00	10 ug 1 mg 2 µg

Rat Breast cancer anti estrogen resistance protein 3(BCAR3) ELISA kit
E02B0756-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Breast cancer anti estrogen resistance protein 3(BCAR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Breast cancer anti estrogen resistance protein 3(BCAR3) ELISA kit
E02B0756-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Breast cancer anti estrogen resistance protein 3(BCAR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Breast cancer anti estrogen resistance protein 3(BCAR3) ELISA kit
E02B0756-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Breast cancer anti estrogen resistance protein 3(BCAR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

ELISA kit for Human BCAR3 (Breast Cancer Anti-Estrogen Resistance 3)
ELK4978	ELK Biotech	1 plate of 96 wells	EUR 518.4
Description: A sandwich ELISA kit for detection of Breast Cancer Anti-Estrogen Resistance 3 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Dog Breast cancer anti estrogen resistance protein 3(BCAR3) ELISA kit
E08B0756-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Breast cancer anti estrogen resistance protein 3(BCAR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Breast cancer anti estrogen resistance protein 3(BCAR3) ELISA kit
E08B0756-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Breast cancer anti estrogen resistance protein 3(BCAR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Breast cancer anti estrogen resistance protein 3(BCAR3) ELISA kit
E08B0756-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Breast cancer anti estrogen resistance protein 3(BCAR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Breast cancer anti estrogen resistance protein 3(BCAR3) ELISA kit
E07B0756-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Breast cancer anti estrogen resistance protein 3(BCAR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Breast cancer anti estrogen resistance protein 3(BCAR3) ELISA kit
E07B0756-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Breast cancer anti estrogen resistance protein 3(BCAR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Breast cancer anti estrogen resistance protein 3(BCAR3) ELISA kit
E07B0756-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Breast cancer anti estrogen resistance protein 3(BCAR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Breast cancer anti estrogen resistance protein 3(BCAR3) ELISA kit
E06B0756-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Breast cancer anti estrogen resistance protein 3(BCAR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Breast cancer anti estrogen resistance protein 3(BCAR3) ELISA kit
E06B0756-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Breast cancer anti estrogen resistance protein 3(BCAR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Most of the synthesized compounds exhibited high resistance against cancer cells tested. Additionally, tyrosine kinase and barriers PIM1 done for the most active compounds in which the substituent variation through the aryl ring and heterocyclic rings given compound with high activity. Our analysis shows that there is a strong correlation between the structure of the compound and a substituent of the target molecule.