Biomaterials in Chimeric Antigen Receptor T-Cell Process Development

ConspectusChimeric antigen receptor (CAR) T-cell therapy has changed the landscape of cancer treatments, utilizing modified ex vivo autologous T cells to treat relapsed or refractory B-cell leukemia and lymphoma. However, the impact of wider therapy has been limited, in part, the production process is complicated, lengthy, and expensive. Thus, as a T-cell therapy CAR more developed to treat other cancers, continuous innovation in manufacturing cell will be crucial to their successful clinical implementation.

This account, we describe our research efforts using biomaterials to raise three fundamental steps in T-cell manufacturing CAR: (1) isolation, (2) activation, and (3) genetic modification.Recognizing T cell isolation reagent clinically and supply costs a high obstacle, we developed a synthetic DNA aptamer and complementary reversal agent technology that CD8 + T cells isolated label-free with high purity and yield of mononuclear cells of peripheral blood. Spirit, CAR T cells are made of both antibody and T cell-isolated aptamer comparable in therapeutic potential.

Invention and design of other T-cell specific aptamers and corresponding reversal reagents can fully realize the potential of this approach, enabling inexpensive isolation of different T cell populations in a single insulating step.Current some material ex vivo T-cell activation does not accurately mimic the in situ activation of cells T by antigen presenting cells (APC). They are not the same cause expansion of CD4 + and CD8 + T cells, so it requires a separate production of CD4 + and CD8 + CAR T cells for therapeutic infusion calls for balanced composition.

 Biomaterials in Chimeric Antigen Receptor T-Cell Process Development
Biomaterials in Chimeric Antigen Receptor T-Cell Process Development

To address this shortcoming, we designed a panel of cell-templated silica microparticles with a biodegradable supported lipid bilayers that display ligand stimulation of T-cell activation. high fluidity of the membrane, elongated shape, and rugged topography of the surface, all of the properties of endogenous APC, which was found to be a favorable parameter for activation, promote unbiased and efficient CD4 / CD8 T-cell expansion while not severe distinguish cells.

Viral and electroporation-based delivery system gene has many weaknesses. viral vectors are expensive and limited the size of the cargo, while the highly cytotoxic electroporation. Thus, low-cost platform nonviral that transfect T cells with low cytotoxicity and high efficiency required for CAR gene delivery. Our group thus synthesized cationic polymer panels with different architectures and evaluated their abilities T cell transfection.

We identified a comb-shaped polymer formulations were transfected primary T cells with low cytotoxicity, although it was a low transfection efficiency compared to conventional methods. Analysis of intracellular and extracellular barriers to transfection reveal polyplexes low absorption and high endosomal pH in T cells, offensive biological properties and polymers that can further innovation improved.These represent only a few recent developments in the field of biomaterials to address the needs of CAR T cell production. Together, these technologies and their future progress would pave the way for the manufacture of T-cell CAR economical and easy.

Human Cancer PrimaCell4: Breast Tumor Cells

2-96027 1 Kit Ask for price

Cancer Antigen CA 15-3 Protein (Human Milk)

VAng-Wyb8631-inquire inquire Ask for price
Description: CA 15-3 (Breast Cancer Antigen), Antigen Grade, Cancer antigen from Human Milk, 33.0 kIU/mL.

Cancer Antigen CA 15-3 Protein (Human Fluids)

VAng-Wyb8628-inquire inquire Ask for price
Description: CA 15-3 (Breast Cancer Antigen), Cancer antigen from Human Fluids, 12.240 kU/mL.

OAEF00048-1MG - Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody

OAEF00048-1MG 1mg
EUR 1112

OAEF00234-1MG - Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody

OAEF00234-1MG 1mg
EUR 279

OAEF00235-1MG - Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody

OAEF00235-1MG 1mg
EUR 279

OAEF00905-1MG - Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody

OAEF00905-1MG 1mg
EUR 1004

OAEF00906-1MG - Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody

OAEF00906-1MG 1mg
EUR 919

Human Cancer PrimaCell4: Breast Tumor Cells Growth Medium

9-46027 5 x 100 ml Ask for price

Breast cancer and normal tissue array with stage and grade info

BR8012 each
EUR 306
Description: Breast cancer and normal tissue array with stage and grade info, 40 cases/80 cores, replaced by BR8014

Breast Cancer-Associated Antigen BRCAA1 (BRCAA1) Antibody

20-abx148333
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

BSA (Standard Grade)

30-AB70 1 kg
EUR 1078.8
Description: Standard Grade Bovine Serum Albumin (99% pure)

Human Cancer Tissue Preparation Buffer 4: Breast Tumor Cells

9-80027 1 x 100 ml Ask for price

OPMA04167-50KIU - Human Cancer Antigen CA15-3 Antigen Grade Protein

OPMA04167-50KIU 50KU
EUR 2999

Human tumor marker CA549 for breast cancer ELISA Kit

SL3271Hu 96 Tests
EUR 468

(untagged)-Human breast cancer antigen NY-BR-1.1 mRNA, partial cds

SC315066 10 µg Ask for price

Cancer Antigen 15-3 MUC 1 Antigen (Human Milk)

VAng-Cr3871-10kU 10 kU
EUR 505.2
Description: Cancer Antigen 15-3 MUC 1 Antigen, Host/Source: Human Milk. The purity is detected by salt extraction and delipidization following high speed centrifugation. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

Breast Cancer and 8 types of tumor (middle advanced stage)tissue array

BR20838a each
EUR 474
Description: Breast Cancer and 8 types of tumor (middle advanced stage)tissue array, including pathology grade, TNM/stage with IHC Her-2 results, 118 cases/208 cores (core size 1.5mm), replacing BR20838

Cancer Antigen 15-3 (CA15-3) (human) ELISA Kit

K4804-100 100 assays
EUR 1000.8
Description: Sensitive, Colorimetric Assay

Florisil@ -200 Mesh Standard Grade

F01454 100G
EUR 229.1

GWB-C9AE54-1MG - Cancer antigen 15-3 Antibody

GWB-C9AE54-1MG 1mg
EUR 389

Cancer Antigen 15-3 MUC 1 Antigen (Human Ascites Fluid)

VAng-Cr3872-10kU 10 kU
EUR 1363.2
Description: Cancer Antigen 15-3 MUC 1 Antigen, Host/Source: Human Ascites Fluid.

Breast tumor tissue array (15 of 25)

BR20821 each
EUR 474
Description: Breast tumor tissue array (15 of 25), including TNM, clinical stage, pathology grade and IHC markers (ER, PR, Her-2) results,104 cases/208 cores

Breast Tumor Tissue Array - 16 cases of breast cancer, each in duplicates, paired with adjacent normal tissues

Z7020007 5 slides
EUR 1657.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Circulating tumor cell breast cancer detection kit (anti-HER-2 Ab Magbeads)

E601CM003 20 tests
EUR 2500

Proteinase K, Recombinant, Standard Grade

9250-100 each
EUR 124.8

Proteinase K, Recombinant, Standard Grade

9250-10G each
EUR 4627.2

Proteinase K, Recombinant, Standard Grade

9250-1G each
EUR 548.4

Proteinase K, Recombinant, Standard Grade

9250-500 each
EUR 314.4

Proteinase K, Recombinant, Standard Grade

9251-100 each
EUR 1266

Proteinase K, Recombinant, Standard Grade

9251-25 each
EUR 352.8

Proteinase K, Recombinant, Standard Grade

9251-5 each
EUR 144

Breast cancer

BR1008b each
EUR 306
Description: Breast cancer, lymph node metastatic carcinoma and adjacent normal tissue array, including pathology grade, TNM, clinical stage, and ER/PR/Her2 result, 100 cases/100 cores, replacing BR1008a

Breast cancer

BR724 each
EUR 270
Description: Breast cancer, adjacent and adjacent normal tissue array, 66 cases/72 cores

Breast cancer

BR725 each
EUR 270
Description: Breast cancer, adjacent and adjacent normal tissue array, 68 cases/72 cores

Breast cancer with cancer adjacent breast tissue array

BC081116e each
EUR 306
Description: Breast cancer with cancer adjacent breast tissue array, including invasive carcinoma of no special type, breast carcinoma with apocrine differentiation and AT tissue,pat hology grade, IHC (ER/PR/Her-2/Ki67) info, TNM/Stage (AJCC 7th edition), 107 cases/110 cores (core size 1.5mm), replacing BC081116d

(untagged)-Human serologically defined breast cancer antigen NY-BR-96 mRNA, complete cds

SC313428 10 µg Ask for price

CancerSeq™ Paraffin Tissue Tumor Block: Breast

T2235086-SB 1 Block
EUR 4014

CancerSeq™ Paraffin Tissue Tumor Slides: Breast

T2235086-ST 5 Slides
EUR 572

Human AFP Antigen Standard

HPX994S 96 Tests
EUR 95

Human CRP Antigen Standard

HPX995S 96 Tests
EUR 100

Breast Tumor Tissue Array - duplicated 70 cases covering all the common types of breast cancer and 5 cases of normal and

Z7020004 5 slides
EUR 1293

Breast Tumor Tissue Array - Duplicated 70 cases covering all the common types of breast cancer and 5 cases of normal and

Z7020005 5 slides
EUR 1293

Breast Tumor Tissue Array - Duplicated 36 cases covering all the common types of breast cancer and 12 cases of normal an

Z7020008 5 slides
EUR 1657.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Breast Tumor Tissue Array - Duplicated 36 cases covering all the common types of breast cancer and 12 cases of normal an

Z7020009 5 slides
EUR 1657.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Human Cancer PrimaCell4: Breast Tumor Cells Growth Supplements with Serum (for 500 ml medium)

9-47027 1 Set Ask for price

CA 15-3, Human Breast Adenocarcinoma

P1435-1 each
EUR 130.8

CA 15-3, Human Breast Adenocarcinoma

P1435-5 each
EUR 288

Breast cancer with matched cancer adjacent breast tissue array

BR804b each
EUR 306
Description: Breast cancer with matched cancer adjacent breast tissue array, including pathology grade, TNM, clinical stage and IHC markers (ER, PR, Her-2 and Ki67), 40 cases/80 cores, replacing BR804a

Standard grade heat shock BSA powder, pH 7

BAH62-0050 50gm
EUR 308.88

Standard grade heat shock BSA powder, pH 7

BAH62-0100 100gm
EUR 388.44

Standard grade heat shock BSA powder, pH 7

BAH62-0500 500gm
EUR 511.68

Standard grade heat shock BSA powder, pH 7

BAH62-1000 1KG Ask for price

Standard grade heat shock BSA powder, pH 7

BAH62-10000 10KG Ask for price

Standard grade heat shock BSA powder, pH 5.2

BAH63-0050 50gm
EUR 308.88

Standard grade heat shock BSA powder, pH 5.2

BAH63-0100 100gm
EUR 388.44

Standard grade heat shock BSA powder, pH 5.2

BAH63-0500 500gm
EUR 511.68

Standard grade heat shock BSA powder, pH 5.2

BAH63-1000 1KG Ask for price

Standard grade heat shock BSA powder, pH 5.2

BAH63-10000 10KG Ask for price

Breast cancer TMA

BR602 each
EUR 270
Description: Breast cancer TMA, 3 samples have matched cancer adjacent tissue samples, including pathology grade, TNM and clinical stage (reference AJCC 8th version), 57 cases/60 cores (Core Size 1.5mm), recent tear collections

Bovine Serum Albumin, Fraction V - Standard Grade

22070008-1 25 g
EUR 44.19
Description: BSA

Bovine Serum Albumin, Fraction V - Standard Grade

22070008-2 50 g
EUR 68.62
Description: BSA

Bovine Serum Albumin, Fraction V - Standard Grade

22070008-3 100 g
EUR 127.13
Description: BSA

Bovine Serum Albumin, Fraction V - Standard Grade

22070008-4 250 g
EUR 248.48
Description: BSA

Bovine Serum Albumin, Fraction V - Standard Grade

22070008-5 500 g
EUR 447.06
Description: BSA

Bovine Serum Albumin, Fraction V - Standard Grade

22070008-6 1 kg
EUR 774.79
Description: BSA

Human LL-37 Antigen Standard

HPX997S 96 Tests
EUR 95

Human Adiponectin Antigen Standard

HPX996S 96 Tests
EUR 95

Microplate cell grade 96well ps standard

781965 PK50
EUR 410.4

CancerSeq™ Plus Paraffin Tissue Tumor Sections: Breast

T2235086-SC 5 curls
EUR 779

Breast cancer with breast tissue array

BC08118a each
EUR 258
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical stage, 100 cases/100 cores (core size 1.0mm), replacing BC08118

Breast cancer with breast tissue array

BR2085d each
EUR 546
Description: Breast cancer with breast tissue array, including pathology grad, TNM and clinical stage, 188 cases/208 cores, replacing BR2085c

Breast cancer with breast tissue array

BR246d each
EUR 66
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical stage (reference AJCC 7th version), 12 cases/24 cores, replacing BR246c

Breast cancer with breast tissue array

BR482 each
EUR 198
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical stage, 24 cases/48 cores

Breast cancer with breast tissue array

BR720 each
EUR 270
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical satge (reference AJCC 7th version), 72 cases/72 cores

Breast cancer with breast tissue array

T087d each
EUR 66
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T087c

Breast cancer with breast tissue array

T088d each
EUR 66
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T088c

Breast Cancer Exosome

P141-BR - Ask for price

Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody

20-abx171475
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody

20-abx324781
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody

20-abx129227
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ovarian Cancer Antigen (CA 125)

CA1251-N-10 10 KU
EUR 634.8

Breast cancer tissue array with cancer adjacent breast tissue as control

BR208a each
EUR 474
Description: Breast cancer tissue array with cancer adjacent breast tissue as control, including TNM, clinical stage and pathology grade, 69 cases/ 207 cores.

Breast cancer (including one case of male breast cancer) with adjacent normal breast tissue array

BC081120g each
EUR 306
Description: Breast cancer (including one case of male breast cancer) with adjacent normal breast tissue array, including pathology grade, TNM and clinical stage (AJCC 7th edition) with IHC results ER/PR/Her2/Ki67,110 cases/110 cores (core size 1.0 mm), replacing BC081120f

Recombinant Breast Cancer Anti-Estrogen Resistance 3 (BCAR3)

4-RPG768Hu01
  • EUR 601.69
  • EUR 284.40
  • EUR 1926.34
  • EUR 722.11
  • EUR 1324.22
  • EUR 477.60
  • EUR 4635.84
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Breast Cancer Anti-Estrogen Resistance 3 expressed in: E.coli

Recombinant Breast Cancer Anti-Estrogen Resistance 3 (BCAR3)

RPU53453-100ug 100ug
EUR 552.2

Recombinant Breast Cancer Anti-Estrogen Resistance 3 (BCAR3)

RPU53453-1mg 1mg
EUR 2446.6

Recombinant Breast Cancer Anti-Estrogen Resistance 3 (BCAR3)

RPU53453-50ug 50ug
EUR 443.3

Bovine Serum Albumin ? Heat Shock, Standard Grade, pH 7.0

7915-100 each
EUR 705.6

Bovine Serum Albumin ? Heat Shock, Standard Grade, pH 7.0

7915-25 each
EUR 274.8

Bovine Serum Albumin ? Heat Shock, Standard Grade, pH 7.0

7915-5 each
EUR 144

Bovine Serum Albumin ? Heat Shock, Standard Grade, pH 5.2

7916-100 each
EUR 705.6

Bovine Serum Albumin ? Heat Shock, Standard Grade, pH 5.2

7916-25 each
EUR 274.8

Bovine Serum Albumin ? Heat Shock, Standard Grade, pH 5.2

7916-5 each
EUR 144

Vitamin A Reference Standard (USP grade powder)

51R-U716002 10 pack
EUR 619.2
Description: Vitamin A Reference Standard (USP grade powder) chemical reference substance

Breast cancer with matched breast tissue array

BR251e each
EUR 60
Description: Breast cancer with matched breast tissue array, including pathology grade, IHC info (ER,PR,Her-2,Ki67),TNM\Stage, 6 cases/24 cores (core size 1.5mm), replacing BR251d

Multiple breast cancer with breast tissue array

BR087e each
EUR 48
Description: Multiple breast cancer with breast tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing BR087d

Human Serum AB off clot Standard Grade Heat Inactivated

S101BHIEU 100ML
EUR 449.16

Cancer of the breast, 75 cases (1.1mm), set 3

BRC1503 1
EUR 300
Description: Breast cancer tissue array, set 3, non-overlapping with BRC1501, BRC1502, BRC1504 to BRC15011,150 cores from normal/benign (5 cases) and cancer (70 cases) tissues in duplicates with grading, TNM staging data, AR, ER, PR, HER2, P53, EGFR, Ki67 IHC data.

Breast Cancer Exosome RNA

P241-BR - Ask for price

Breast cancer tissue array

BR042b each
EUR 78
Description: Breast cancer tissue array, including TNM and pathology grade, 4 cases/4 cores, replacing BR042a

Breast cancer tissue array

BR1006a each
EUR 306
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, 50 cases/100 cores (core size 1.0mm), replacing BR1006

Breast cancer tissue array

BR1141a each
EUR 354
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, IHC marker (ER, PR, HER2 and Ki-67), 114 cases/114 cores, replacing BR1141

Breast cancer tissue array

BR1401 each
EUR 414
Description: Breast cancer tissue array, including TNM and pathology grade, IHC markers ER/PR/Her-2 results, 140 cases/140 cores (core size 1.0mm)

Breast cancer tissue array

BR1503f each
EUR 306
Description: Breast cancer tissue array, including TNM and pathology grade, with IHC results of Her-2\ER\PR\Ki67, 75 cases/ 150 cores, replacing BR1503e

Breast cancer tissue array

BR1505e each
EUR 306
Description: Breast cancer tissue array, including pathology grade, TNM, clinical stage, and IHC(HER2/ER/PR/Ki67), 75 cases/150 cores, replacing BR1505d

Breast cancer tissue array

BR2161 each
EUR 546
Description: Breast cancer tissue array, including TNM and pathology grade, 216 cases/216 cores

Breast cancer tissue array

BR247a each
EUR 234
Description: Breast cancer tissue array, with normal tissue, including TNM and pathology grade, IHC marker (HER2), 24 cases/48 cores replacing BR247

Breast cancer tissue array

BR488 each
EUR 306
Description: Breast cancer tissue array, including pathology grade, TNM, clinical stage (AJCC 7th edition), and IHC marker(ER,PR,Her-2), 48 cases/48 cores

Breast cancer tissue array

BR501 each
EUR 270
Description: Breast cancer tissue array, including TNM and pathology grade, 50 cases/ 50 cores (core size 1.5mm)

Breast cancer tissue array

BR8015a each
EUR 306
Description: Breast cancer tissue array, with adjacent normal tissue and normal tissue, including TNM and pathology grade, 80 cases/80 cores, replacing BC08014

Breast cancer tissue array

BR964 each
EUR 222
Description: Breast cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/96 cores

Breast cancer tissue array

T089c each
EUR 48
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores(1.5mm), replacing T089b

Human Breast Cancer HS0001

HS0001 6 Slides/Pack
EUR 160

Human Breast Cancer HS0002

HS0002 6 Slides/Pack
EUR 160

Human Breast Cancer HS0003

HS0003 6 Slides/Pack
EUR 160

Human Breast Cancer HS0004

HS0004 6 Slides/Pack
EUR 160

Human Breast Cancer HS0005

HS0005 6 Slides/Pack
EUR 160

Cancer Antigen CA-125 Antigen (Human Fluids)

VAng-Wyb8639-inquire inquire Ask for price
Description: CA-125, Calibrator Grade, cancer antigen from Human Fluids, 53.26 KU/mL.

Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Protein

20-abx168253
  • EUR 844.80
  • EUR 343.20
  • EUR 2598.00
  • EUR 994.80
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Breast Cancer-Associated Gene 3 Protein (BCA3) Antibody

20-abx133658
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Breast Cancer-Associated Gene 3 Protein (BCA3) Antibody

abx025588-400ul 400 ul
EUR 627.6

Breast Cancer-Associated Gene 3 Protein (BCA3) Antibody

abx025588-80l 80 µl
EUR 343.2

Breast Cancer-Associated Gene 3 Protein (BCA3) Antibody

20-abx013807
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Advanced stage breast cancer and normal breast tissue array

BR1191 each
EUR 306
Description: Advanced stage breast cancer and normal breast tissue array, including pathology grade, TNM and clinical stage (AJCC 8.0), ER\PR\HER-2\Ki-67 marker, 119 cases/119 cores, (1.5mm)

Breast Cancer Anti-Estrogen Resistance Protein 3 (BCAR3) Antibody

20-abx134976
  • EUR 427.20
  • EUR 644.40
  • EUR 260.40
  • 100 ul
  • 200 ul
  • 30 ul

Breast Cancer Anti-Estrogen Resistance Protein 3 (BCAR3) Antibody

abx218562-100ug 100 ug
EUR 526.8

Breast Cancer Anti-Estrogen Resistance Protein 3 (BCAR3) Antibody

abx432398-200ul 200 ul
EUR 460.8

Breast Cancer Anti-Estrogen Resistance Protein 3 (BCAR3) Antibody

abx010337-100ug 100 ug
EUR 526.8

Cancer Antigen CA 19-9 Antibody

abx023798-1mg 1 mg
EUR 1053.6

Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Polyclonal Antibody

CAU22164-100ul 100ul
EUR 235.2

Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Polyclonal Antibody

CAU22164-200ul 200ul
EUR 294

Breast normal tissue with breast cancer tissue array

BRN801c each
EUR 270
Description: Breast normal tissue with breast cancer tissue array, including pathology grade, TNM and clinical stage, 80 cases/80 cores, replacing BRN801b

Cancer Antigen CA-125 Antigen (Human Adenocarcinoma)

VAng-Wyb8642-inquire inquire Ask for price
Description: CA-125, Calibrator Grade, Cancer antigen from Human Adenocarcinoma, 500 kIU / mL.

Most of the synthesized compounds exhibited high resistance against cancer cells tested. Additionally, tyrosine kinase and barriers PIM1 done for the most active compounds in which the substituent variation through the aryl ring and heterocyclic rings given compound with high activity. Our analysis shows that there is a strong correlation between the structure of the compound and a substituent of the target molecule.