ConspectusChimeric antigen receptor (CAR) T-cell therapy has changed the landscape of cancer treatments, utilizing modified ex vivo autologous T cells to treat relapsed or refractory B-cell leukemia and lymphoma. However, the impact of wider therapy has been limited, in part, the production process is complicated, lengthy, and expensive. Thus, as a T-cell therapy CAR more developed to treat other cancers, continuous innovation in manufacturing cell will be crucial to their successful clinical implementation.
This account, we describe our research efforts using biomaterials to raise three fundamental steps in T-cell manufacturing CAR: (1) isolation, (2) activation, and (3) genetic modification.Recognizing T cell isolation reagent clinically and supply costs a high obstacle, we developed a synthetic DNA aptamer and complementary reversal agent technology that CD8 + T cells isolated label-free with high purity and yield of mononuclear cells of peripheral blood. Spirit, CAR T cells are made of both antibody and T cell-isolated aptamer comparable in therapeutic potential.
Invention and design of other T-cell specific aptamers and corresponding reversal reagents can fully realize the potential of this approach, enabling inexpensive isolation of different T cell populations in a single insulating step.Current some material ex vivo T-cell activation does not accurately mimic the in situ activation of cells T by antigen presenting cells (APC). They are not the same cause expansion of CD4 + and CD8 + T cells, so it requires a separate production of CD4 + and CD8 + CAR T cells for therapeutic infusion calls for balanced composition.
Biomaterials in Chimeric Antigen Receptor T-Cell Process Development
To address this shortcoming, we designed a panel of cell-templated silica microparticles with a biodegradable supported lipid bilayers that display ligand stimulation of T-cell activation. high fluidity of the membrane, elongated shape, and rugged topography of the surface, all of the properties of endogenous APC, which was found to be a favorable parameter for activation, promote unbiased and efficient CD4 / CD8 T-cell expansion while not severe distinguish cells.
Viral and electroporation-based delivery system gene has many weaknesses. viral vectors are expensive and limited the size of the cargo, while the highly cytotoxic electroporation. Thus, low-cost platform nonviral that transfect T cells with low cytotoxicity and high efficiency required for CAR gene delivery. Our group thus synthesized cationic polymer panels with different architectures and evaluated their abilities T cell transfection.
We identified a comb-shaped polymer formulations were transfected primary T cells with low cytotoxicity, although it was a low transfection efficiency compared to conventional methods. Analysis of intracellular and extracellular barriers to transfection reveal polyplexes low absorption and high endosomal pH in T cells, offensive biological properties and polymers that can further innovation improved.These represent only a few recent developments in the field of biomaterials to address the needs of CAR T cell production. Together, these technologies and their future progress would pave the way for the manufacture of T-cell CAR economical and easy.
Cancer Antigen 72-4 (CA 72-4) Standard Grade
GWB-254330
GenWay Biotech
50000 Unit
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Cancer Antigen 19-9 (CA 19-9) Standard Grade
GWB-1CA918
GenWay Biotech
50000 Unit
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Cancer Antigen 19-9 (CA 19-9) Standard Grade
GWB-EECE0C
GenWay Biotech
50000 Unit
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Cancer Antigen 15-3 (CA 15-3) Low Cross Grade
GWB-E47BC0
GenWay Biotech
10000 Unit
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CA15-3 Cancer Antigen (CA15-3, Breast Tumor Protein)
MBS651681-10KUnits
MyBiosource
10KUnits
EUR 1050
CA15-3 Cancer Antigen (CA15-3, Breast Tumor Protein)
MBS651681-5x10KUnits
MyBiosource
5x10KUnits
EUR 4565
Cancer Antigen 15-3 (CA 15-3) Cell Culture Low Cross Grade
GWB-553B7B
GenWay Biotech
10000 Unit
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Breast tumor antigen (CA-15-3) Antibody, Concentrate
MAB521C
Innovex
0.2ml
EUR 455
Breast tumor antigen (CA-15-3) Antibody, Ready-To-Use
MAB521P
Innovex
5ml
EUR 445
CA15-3 Cancer Antigen (Breast Cancer)
MBS651656-50KUnits
MyBiosource
50KUnits
EUR 1890
CA15-3 Cancer Antigen (Breast Cancer)
MBS651656-5x50KUnits
MyBiosource
5x50KUnits
EUR 8345
Cancer Antigen 15-3 (CA 15-3)
MBS173320-1000Units
MyBiosource
1000Units
EUR 205
Cancer Antigen 15-3 (CA 15-3)
MBS173320-25KUnits
MyBiosource
25KUnits
EUR 950
Cancer Antigen 15-3 (CA 15-3)
MBS173320-5000Units
MyBiosource
5000Units
EUR 350
Cancer Antigen 15-3 (CA 15-3)
MBS173320-5x25KUnits
MyBiosource
5x25KUnits
EUR 4070
Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody Pair Kit (with Standard)
MBS2103664-10x96Tests
MyBiosource
10x96Tests
EUR 1480
Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody Pair Kit (with Standard)
MBS2103664-10x96TestsMBS2090685AbPairsSupportPack110x96Tests
MyBiosource
10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1600
Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody Pair Kit (with Standard)
MBS2103664-5x96Tests
MyBiosource
5x96Tests
EUR 935
Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody Pair Kit (with Standard)
MBS2103664-5x96TestsMBS2090685AbPairsSupportPack15x96Tests
MyBiosource
5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 1010
Cancer Antigen (CA) 15-3 ELISA
GWB-BQK041
GenWay Biotech
96 Well Plate
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Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody
MBS5680048-1mg
MyBiosource
1mg
EUR 1040
Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody
MBS5680048-5x1mg
MyBiosource
5x1mg
EUR 4480
Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody
MBS5680049-1mg
MyBiosource
1mg
EUR 1040
Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody
MBS5680049-5x1mg
MyBiosource
5x1mg
EUR 4480
Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody
MBS5680050-1mg
MyBiosource
1mg
EUR 1040
Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody
MBS5680050-5x1mg
MyBiosource
5x1mg
EUR 4480
Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody
MBS569771-1mg
MyBiosource
1mg
EUR 1040
Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody
MBS569771-5x1mg
MyBiosource
5x1mg
EUR 4480
Human Cancer Antigen 15-3 (CA 15-3) ELISA Kit
PRB-5069
Cell Biolabs
96 assays
EUR 686.4
Human Cancer Antigen 15-3 (CA 15-3) ELISA Kit
PRB-5069-5
Cell Biolabs
5 x 96 assays
EUR 2739.6
Human Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) Antibody Pair Kit (with Standard)
MBS2103665-10x96Tests
MyBiosource
10x96Tests
EUR 1480
Human Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) Antibody Pair Kit (with Standard)
MBS2103665-10x96TestsMBS2090685AbPairsSupportPack110x96Tests
MyBiosource
10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1600
Human Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) Antibody Pair Kit (with Standard)
MBS2103665-5x96Tests
MyBiosource
5x96Tests
EUR 935
Human Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) Antibody Pair Kit (with Standard)
MBS2103665-5x96TestsMBS2090685AbPairsSupportPack15x96Tests
MyBiosource
5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 1010
Human Breast Tumor Cancer Cells
ABC-HP013X
AcceGen
1 vial
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Description: Human breast cancer cells are isolated from human invasive ductal breast carcinoma sample. Human breast cancer cells are positive for pan-Cytokeratin, MGB-1 and MUC-1. CD90 staining shows that cultures are free of fibroblasts in 99%.
OPEF01469-10KU - Cancer Antigen 15-3 (CA 15-3) MUC 1 Antigen
OPEF01469-10KU
Aviva Systems Biology
10kU
EUR 185
Rat Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)
MBS2100267-10x96Tests
MyBiosource
10x96Tests
EUR 1595
Rat Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)
MBS2100267-10x96TestsMBS2090685AbPairsSupportPack110x96Tests
MyBiosource
10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1715
Rat Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)
MBS2100267-5x96Tests
MyBiosource
5x96Tests
EUR 1005
Rat Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)
MBS2100267-5x96TestsMBS2090685AbPairsSupportPack15x96Tests
MyBiosource
5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 1080
Rat Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)
MBS2100292-10x96Tests
MyBiosource
10x96Tests
EUR 1595
Rat Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)
MBS2100292-10x96TestsMBS2090685AbPairsSupportPack110x96Tests
MyBiosource
10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1715
Rat Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)
MBS2100292-5x96Tests
MyBiosource
5x96Tests
EUR 1005
Rat Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)
MBS2100292-5x96TestsMBS2090685AbPairsSupportPack15x96Tests
MyBiosource
5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 1080
Gastrointestinal Cancer Antigen (CA 19-9), antigen grade
CA1991-N-10
Alpha Diagnostics
10 KU
EUR 634.8
Human Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)
MBS2100265-10x96Tests
MyBiosource
10x96Tests
EUR 1410
Human Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)
MBS2100265-10x96TestsMBS2090685AbPairsSupportPack110x96Tests
MyBiosource
10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1530
Human Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)
MBS2100265-5x96Tests
MyBiosource
5x96Tests
EUR 895
Human Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)
MBS2100265-5x96TestsMBS2090685AbPairsSupportPack15x96Tests
MyBiosource
5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 970
Mouse Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)
MBS2100266-10x96Tests
MyBiosource
10x96Tests
EUR 1445
Mouse Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)
MBS2100266-10x96TestsMBS2090685AbPairsSupportPack110x96Tests
MyBiosource
10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1570
Mouse Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)
MBS2100266-5x96Tests
MyBiosource
5x96Tests
EUR 915
Mouse Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)
MBS2100266-5x96TestsMBS2090685AbPairsSupportPack15x96Tests
MyBiosource
5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 990
Human Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)
MBS2100290-10x96Tests
MyBiosource
10x96Tests
EUR 1410
Human Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)
MBS2100290-10x96TestsMBS2090685AbPairsSupportPack110x96Tests
MyBiosource
10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1530
Human Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)
MBS2100290-5x96Tests
MyBiosource
5x96Tests
EUR 895
Human Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)
MBS2100290-5x96TestsMBS2090685AbPairsSupportPack15x96Tests
MyBiosource
5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 970
Mouse Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)
MBS2100291-10x96Tests
MyBiosource
10x96Tests
EUR 1515
Mouse Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)
MBS2100291-10x96TestsMBS2090685AbPairsSupportPack110x96Tests
MyBiosource
10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1640
Mouse Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)
MBS2100291-5x96Tests
MyBiosource
5x96Tests
EUR 960
Mouse Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)
MBS2100291-5x96TestsMBS2090685AbPairsSupportPack15x96Tests
MyBiosource
5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 1035
Human Cancer Antigen CA15-3 Antigen Grade
GWB-C54ECC
GenWay Biotech
50000 Unit
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Human Cancer Antigen CA15-3 Antigen Grade
MBS318065-50KUnits
MyBiosource
50KUnits
EUR 2585
Human Cancer Antigen CA15-3 Antigen Grade
MBS318065-5x50KUnits
MyBiosource
5x50KUnits
EUR 11460
Cancer Antigen 15-3 (CA 15-3) Cell Culture High Purity
GWB-1A625F
GenWay Biotech
10000 Unit
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Cancer Antigen 125 (CA 125) Low Cross Grade
GWB-87F2DB
GenWay Biotech
10000 Unit
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MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401307-01mL
MyBiosource
0.1mL
EUR 1040
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401307-5x01mL
MyBiosource
5x0.1mL
EUR 4540
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401308-01mL
MyBiosource
0.1mL
EUR 1040
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401308-5x01mL
MyBiosource
5x0.1mL
EUR 4540
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401309-01mL
MyBiosource
0.1mL
EUR 1040
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401309-5x01mL
MyBiosource
5x0.1mL
EUR 4540
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401310-01mL
MyBiosource
0.1mL
EUR 1040
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401310-5x01mL
MyBiosource
5x0.1mL
EUR 4540
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401311-01mL
MyBiosource
0.1mL
EUR 1040
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401311-5x01mL
MyBiosource
5x0.1mL
EUR 4540
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401312-01mL
MyBiosource
0.1mL
EUR 1040
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401312-5x01mL
MyBiosource
5x0.1mL
EUR 4540
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401313-01mL
MyBiosource
0.1mL
EUR 1040
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401313-5x01mL
MyBiosource
5x0.1mL
EUR 4540
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401314-01mL
MyBiosource
0.1mL
EUR 1040
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401314-5x01mL
MyBiosource
5x0.1mL
EUR 4540
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401315-01mL
MyBiosource
0.1mL
EUR 1040
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401315-5x01mL
MyBiosource
5x0.1mL
EUR 4540
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401316-01mL
MyBiosource
0.1mL
EUR 1040
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401316-5x01mL
MyBiosource
5x0.1mL
EUR 4540
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401317-01mL
MyBiosource
0.1mL
EUR 1040
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6401317-5x01mL
MyBiosource
5x0.1mL
EUR 4540
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6260380-01mL
MyBiosource
0.1mL
EUR 970
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6260380-5x01mL
MyBiosource
5x0.1mL
EUR 4220
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6260381-01mL
MyBiosource
0.1mL
EUR 970
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6260381-5x01mL
MyBiosource
5x0.1mL
EUR 4220
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6260382-01mL
MyBiosource
0.1mL
EUR 1185
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6260382-5x01mL
MyBiosource
5x0.1mL
EUR 5180
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6260383-01mL
MyBiosource
0.1mL
EUR 1185
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6260383-5x01mL
MyBiosource
5x0.1mL
EUR 5180
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6263953-01mL
MyBiosource
0.1mL
EUR 970
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6263953-5x01mL
MyBiosource
5x0.1mL
EUR 4220
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6263954-01mL
MyBiosource
0.1mL
EUR 970
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6263954-5x01mL
MyBiosource
5x0.1mL
EUR 4220
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6263955-01mL
MyBiosource
0.1mL
EUR 1185
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6263955-5x01mL
MyBiosource
5x0.1mL
EUR 5180
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6263956-01mL
MyBiosource
0.1mL
EUR 1185
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6263956-5x01mL
MyBiosource
5x0.1mL
EUR 5180
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264464-01mL
MyBiosource
0.1mL
EUR 970
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264464-5x01mL
MyBiosource
5x0.1mL
EUR 4220
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264465-01mL
MyBiosource
0.1mL
EUR 970
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264465-5x01mL
MyBiosource
5x0.1mL
EUR 4220
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264466-01mL
MyBiosource
0.1mL
EUR 1185
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264466-5x01mL
MyBiosource
5x0.1mL
EUR 5180
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264467-01mL
MyBiosource
0.1mL
EUR 1185
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264467-5x01mL
MyBiosource
5x0.1mL
EUR 5180
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264975-01mL
MyBiosource
0.1mL
EUR 970
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264975-5x01mL
MyBiosource
5x0.1mL
EUR 4220
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264976-01mL
MyBiosource
0.1mL
EUR 970
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264976-5x01mL
MyBiosource
5x0.1mL
EUR 4220
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264977-01mL
MyBiosource
0.1mL
EUR 1185
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264977-5x01mL
MyBiosource
5x0.1mL
EUR 5180
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264978-01mL
MyBiosource
0.1mL
EUR 1185
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6264978-5x01mL
MyBiosource
5x0.1mL
EUR 5180
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6265486-01mL
MyBiosource
0.1mL
EUR 970
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6265486-5x01mL
MyBiosource
5x0.1mL
EUR 4220
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6265487-01mL
MyBiosource
0.1mL
EUR 970
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6265487-5x01mL
MyBiosource
5x0.1mL
EUR 4220
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6265488-01mL
MyBiosource
0.1mL
EUR 1185
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6265488-5x01mL
MyBiosource
5x0.1mL
EUR 5180
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6265489-01mL
MyBiosource
0.1mL
EUR 1185
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6265489-5x01mL
MyBiosource
5x0.1mL
EUR 5180
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6261910-01mL
MyBiosource
0.1mL
EUR 970
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6261910-5x01mL
MyBiosource
5x0.1mL
EUR 4220
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6261911-01mL
MyBiosource
0.1mL
EUR 970
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6261911-5x01mL
MyBiosource
5x0.1mL
EUR 4220
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6261912-01mL
MyBiosource
0.1mL
EUR 1185
MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass
MBS6261912-5x01mL
MyBiosource
5x0.1mL
EUR 5180
Most of the synthesized compounds exhibited high resistance against cancer cells tested. Additionally, tyrosine kinase and barriers PIM1 done for the most active compounds in which the substituent variation through the aryl ring and heterocyclic rings given compound with high activity. Our analysis shows that there is a strong correlation between the structure of the compound and a substituent of the target molecule.