Biomaterials in Chimeric Antigen Receptor T-Cell Process Development

ConspectusChimeric antigen receptor (CAR) T-cell therapy has changed the landscape of cancer treatments, utilizing modified ex vivo autologous T cells to treat relapsed or refractory B-cell leukemia and lymphoma. However, the impact of wider therapy has been limited, in part, the production process is complicated, lengthy, and expensive. Thus, as a T-cell therapy CAR more developed to treat other cancers, continuous innovation in manufacturing cell will be crucial to their successful clinical implementation.

This account, we describe our research efforts using biomaterials to raise three fundamental steps in T-cell manufacturing CAR: (1) isolation, (2) activation, and (3) genetic modification.Recognizing T cell isolation reagent clinically and supply costs a high obstacle, we developed a synthetic DNA aptamer and complementary reversal agent technology that CD8 + T cells isolated label-free with high purity and yield of mononuclear cells of peripheral blood. Spirit, CAR T cells are made of both antibody and T cell-isolated aptamer comparable in therapeutic potential.

Invention and design of other T-cell specific aptamers and corresponding reversal reagents can fully realize the potential of this approach, enabling inexpensive isolation of different T cell populations in a single insulating step.Current some material ex vivo T-cell activation does not accurately mimic the in situ activation of cells T by antigen presenting cells (APC). They are not the same cause expansion of CD4 + and CD8 + T cells, so it requires a separate production of CD4 + and CD8 + CAR T cells for therapeutic infusion calls for balanced composition.

 Biomaterials in Chimeric Antigen Receptor T-Cell Process Development
Biomaterials in Chimeric Antigen Receptor T-Cell Process Development

To address this shortcoming, we designed a panel of cell-templated silica microparticles with a biodegradable supported lipid bilayers that display ligand stimulation of T-cell activation. high fluidity of the membrane, elongated shape, and rugged topography of the surface, all of the properties of endogenous APC, which was found to be a favorable parameter for activation, promote unbiased and efficient CD4 / CD8 T-cell expansion while not severe distinguish cells.

Viral and electroporation-based delivery system gene has many weaknesses. viral vectors are expensive and limited the size of the cargo, while the highly cytotoxic electroporation. Thus, low-cost platform nonviral that transfect T cells with low cytotoxicity and high efficiency required for CAR gene delivery. Our group thus synthesized cationic polymer panels with different architectures and evaluated their abilities T cell transfection.

We identified a comb-shaped polymer formulations were transfected primary T cells with low cytotoxicity, although it was a low transfection efficiency compared to conventional methods. Analysis of intracellular and extracellular barriers to transfection reveal polyplexes low absorption and high endosomal pH in T cells, offensive biological properties and polymers that can further innovation improved.These represent only a few recent developments in the field of biomaterials to address the needs of CAR T cell production. Together, these technologies and their future progress would pave the way for the manufacture of T-cell CAR economical and easy.

Cancer Antigen 72-4 (CA 72-4) Standard Grade

GWB-254330 50000 Unit Ask for price

Cancer Antigen 19-9 (CA 19-9) Standard Grade

GWB-1CA918 50000 Unit Ask for price

Cancer Antigen 19-9 (CA 19-9) Standard Grade

GWB-EECE0C 50000 Unit Ask for price

Cancer Antigen 15-3 (CA 15-3) Low Cross Grade

GWB-E47BC0 10000 Unit Ask for price

CA15-3 Cancer Antigen (CA15-3, Breast Tumor Protein)

MBS651681-10KUnits 10KUnits
EUR 1050

CA15-3 Cancer Antigen (CA15-3, Breast Tumor Protein)

MBS651681-5x10KUnits 5x10KUnits
EUR 4565

Cancer Antigen 15-3 (CA 15-3) Cell Culture Low Cross Grade

GWB-553B7B 10000 Unit Ask for price

Breast tumor antigen (CA-15-3) Antibody, Concentrate

MAB521C 0.2ml
EUR 455

Breast tumor antigen (CA-15-3) Antibody, Ready-To-Use

MAB521P 5ml
EUR 445

CA15-3 Cancer Antigen (Breast Cancer)

MBS651656-50KUnits 50KUnits
EUR 1890

CA15-3 Cancer Antigen (Breast Cancer)

MBS651656-5x50KUnits 5x50KUnits
EUR 8345

Cancer Antigen 15-3 (CA 15-3)

MBS173320-1000Units 1000Units
EUR 205

Cancer Antigen 15-3 (CA 15-3)

MBS173320-25KUnits 25KUnits
EUR 950

Cancer Antigen 15-3 (CA 15-3)

MBS173320-5000Units 5000Units
EUR 350

Cancer Antigen 15-3 (CA 15-3)

MBS173320-5x25KUnits 5x25KUnits
EUR 4070

Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody Pair Kit (with Standard)

MBS2103664-10x96Tests 10x96Tests
EUR 1480

Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody Pair Kit (with Standard)

MBS2103664-10x96TestsMBS2090685AbPairsSupportPack110x96Tests 10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1600

Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody Pair Kit (with Standard)

MBS2103664-5x96Tests 5x96Tests
EUR 935

Human Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Antibody Pair Kit (with Standard)

MBS2103664-5x96TestsMBS2090685AbPairsSupportPack15x96Tests 5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 1010

Cancer Antigen (CA) 15-3 ELISA

GWB-BQK041 96 Well Plate Ask for price

Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody

MBS5680048-1mg 1mg
EUR 1040

Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody

MBS5680048-5x1mg 5x1mg
EUR 4480

Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody

MBS5680049-1mg 1mg
EUR 1040

Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody

MBS5680049-5x1mg 5x1mg
EUR 4480

Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody

MBS5680050-1mg 1mg
EUR 1040

Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody

MBS5680050-5x1mg 5x1mg
EUR 4480

Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody

MBS569771-1mg 1mg
EUR 1040

Cancer Antigen 15-3 (CA 15-3) MUC 1 Antibody

MBS569771-5x1mg 5x1mg
EUR 4480

Human Cancer Antigen 15-3 (CA 15-3) ELISA Kit

PRB-5069 96 assays
EUR 686.4

Human Cancer Antigen 15-3 (CA 15-3) ELISA Kit

PRB-5069-5 5 x 96 assays
EUR 2739.6

Human Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) Antibody Pair Kit (with Standard)

MBS2103665-10x96Tests 10x96Tests
EUR 1480

Human Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) Antibody Pair Kit (with Standard)

MBS2103665-10x96TestsMBS2090685AbPairsSupportPack110x96Tests 10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1600

Human Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) Antibody Pair Kit (with Standard)

MBS2103665-5x96Tests 5x96Tests
EUR 935

Human Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) Antibody Pair Kit (with Standard)

MBS2103665-5x96TestsMBS2090685AbPairsSupportPack15x96Tests 5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 1010

Human Breast Tumor Cancer Cells

ABC-HP013X 1 vial Ask for price
Description: Human breast cancer cells are isolated from human invasive ductal breast carcinoma sample. Human breast cancer cells are positive for pan-Cytokeratin, MGB-1 and MUC-1. CD90 staining shows that cultures are free of fibroblasts in 99%.

OPEF01469-10KU - Cancer Antigen 15-3 (CA 15-3) MUC 1 Antigen

OPEF01469-10KU 10kU
EUR 185

Rat Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)

MBS2100267-10x96Tests 10x96Tests
EUR 1595

Rat Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)

MBS2100267-10x96TestsMBS2090685AbPairsSupportPack110x96Tests 10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1715

Rat Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)

MBS2100267-5x96Tests 5x96Tests
EUR 1005

Rat Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)

MBS2100267-5x96TestsMBS2090685AbPairsSupportPack15x96Tests 5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 1080

Rat Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)

MBS2100292-10x96Tests 10x96Tests
EUR 1595

Rat Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)

MBS2100292-10x96TestsMBS2090685AbPairsSupportPack110x96Tests 10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1715

Rat Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)

MBS2100292-5x96Tests 5x96Tests
EUR 1005

Rat Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)

MBS2100292-5x96TestsMBS2090685AbPairsSupportPack15x96Tests 5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 1080

Gastrointestinal Cancer Antigen (CA 19-9), antigen grade

CA1991-N-10 10 KU
EUR 634.8

Human Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)

MBS2100265-10x96Tests 10x96Tests
EUR 1410

Human Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)

MBS2100265-10x96TestsMBS2090685AbPairsSupportPack110x96Tests 10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1530

Human Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)

MBS2100265-5x96Tests 5x96Tests
EUR 895

Human Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)

MBS2100265-5x96TestsMBS2090685AbPairsSupportPack15x96Tests 5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 970

Mouse Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)

MBS2100266-10x96Tests 10x96Tests
EUR 1445

Mouse Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)

MBS2100266-10x96TestsMBS2090685AbPairsSupportPack110x96Tests 10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1570

Mouse Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)

MBS2100266-5x96Tests 5x96Tests
EUR 915

Mouse Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody Pair Kit (with Standard)

MBS2100266-5x96TestsMBS2090685AbPairsSupportPack15x96Tests 5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 990

Human Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)

MBS2100290-10x96Tests 10x96Tests
EUR 1410

Human Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)

MBS2100290-10x96TestsMBS2090685AbPairsSupportPack110x96Tests 10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1530

Human Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)

MBS2100290-5x96Tests 5x96Tests
EUR 895

Human Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)

MBS2100290-5x96TestsMBS2090685AbPairsSupportPack15x96Tests 5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 970

Mouse Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)

MBS2100291-10x96Tests 10x96Tests
EUR 1515

Mouse Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)

MBS2100291-10x96TestsMBS2090685AbPairsSupportPack110x96Tests 10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1640

Mouse Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)

MBS2100291-5x96Tests 5x96Tests
EUR 960

Mouse Breast Cancer Susceptibility Protein 1 (BRCA1) Antibody Pair Kit (with Standard)

MBS2100291-5x96TestsMBS2090685AbPairsSupportPack15x96Tests 5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 1035

Human Cancer Antigen CA15-3 Antigen Grade

GWB-C54ECC 50000 Unit Ask for price

Human Cancer Antigen CA15-3 Antigen Grade

MBS318065-50KUnits 50KUnits
EUR 2585

Human Cancer Antigen CA15-3 Antigen Grade

MBS318065-5x50KUnits 5x50KUnits
EUR 11460

Cancer Antigen 15-3 (CA 15-3) Cell Culture High Purity

GWB-1A625F 10000 Unit Ask for price

Cancer Antigen 125 (CA 125) Low Cross Grade

GWB-87F2DB 10000 Unit Ask for price

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401307-01mL 0.1mL
EUR 1040

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401307-5x01mL 5x0.1mL
EUR 4540

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401308-01mL 0.1mL
EUR 1040

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401308-5x01mL 5x0.1mL
EUR 4540

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401309-01mL 0.1mL
EUR 1040

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401309-5x01mL 5x0.1mL
EUR 4540

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401310-01mL 0.1mL
EUR 1040

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401310-5x01mL 5x0.1mL
EUR 4540

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401311-01mL 0.1mL
EUR 1040

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401311-5x01mL 5x0.1mL
EUR 4540

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401312-01mL 0.1mL
EUR 1040

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401312-5x01mL 5x0.1mL
EUR 4540

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401313-01mL 0.1mL
EUR 1040

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401313-5x01mL 5x0.1mL
EUR 4540

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401314-01mL 0.1mL
EUR 1040

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401314-5x01mL 5x0.1mL
EUR 4540

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401315-01mL 0.1mL
EUR 1040

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401315-5x01mL 5x0.1mL
EUR 4540

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401316-01mL 0.1mL
EUR 1040

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401316-5x01mL 5x0.1mL
EUR 4540

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401317-01mL 0.1mL
EUR 1040

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6401317-5x01mL 5x0.1mL
EUR 4540

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6260380-01mL 0.1mL
EUR 970

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6260380-5x01mL 5x0.1mL
EUR 4220

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6260381-01mL 0.1mL
EUR 970

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6260381-5x01mL 5x0.1mL
EUR 4220

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6260382-01mL 0.1mL
EUR 1185

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6260382-5x01mL 5x0.1mL
EUR 5180

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6260383-01mL 0.1mL
EUR 1185

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6260383-5x01mL 5x0.1mL
EUR 5180

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6263953-01mL 0.1mL
EUR 970

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6263953-5x01mL 5x0.1mL
EUR 4220

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6263954-01mL 0.1mL
EUR 970

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6263954-5x01mL 5x0.1mL
EUR 4220

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6263955-01mL 0.1mL
EUR 1185

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6263955-5x01mL 5x0.1mL
EUR 5180

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6263956-01mL 0.1mL
EUR 1185

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6263956-5x01mL 5x0.1mL
EUR 5180

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264464-01mL 0.1mL
EUR 970

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264464-5x01mL 5x0.1mL
EUR 4220

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264465-01mL 0.1mL
EUR 970

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264465-5x01mL 5x0.1mL
EUR 4220

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264466-01mL 0.1mL
EUR 1185

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264466-5x01mL 5x0.1mL
EUR 5180

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264467-01mL 0.1mL
EUR 1185

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264467-5x01mL 5x0.1mL
EUR 5180

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264975-01mL 0.1mL
EUR 970

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264975-5x01mL 5x0.1mL
EUR 4220

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264976-01mL 0.1mL
EUR 970

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264976-5x01mL 5x0.1mL
EUR 4220

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264977-01mL 0.1mL
EUR 1185

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264977-5x01mL 5x0.1mL
EUR 5180

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264978-01mL 0.1mL
EUR 1185

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6264978-5x01mL 5x0.1mL
EUR 5180

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6265486-01mL 0.1mL
EUR 970

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6265486-5x01mL 5x0.1mL
EUR 4220

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6265487-01mL 0.1mL
EUR 970

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6265487-5x01mL 5x0.1mL
EUR 4220

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6265488-01mL 0.1mL
EUR 1185

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6265488-5x01mL 5x0.1mL
EUR 5180

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6265489-01mL 0.1mL
EUR 1185

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6265489-5x01mL 5x0.1mL
EUR 5180

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6261910-01mL 0.1mL
EUR 970

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6261910-5x01mL 5x0.1mL
EUR 4220

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6261911-01mL 0.1mL
EUR 970

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6261911-5x01mL 5x0.1mL
EUR 4220

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6261912-01mL 0.1mL
EUR 1185

MUC1 (Mucin-1, MUC-1, Breast Carcinoma-associated Antigen DF3, Cancer Antigen 15-3, CA 15-3, Carcinoma-associated Mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, Tumor-ass

MBS6261912-5x01mL 5x0.1mL
EUR 5180

Most of the synthesized compounds exhibited high resistance against cancer cells tested. Additionally, tyrosine kinase and barriers PIM1 done for the most active compounds in which the substituent variation through the aryl ring and heterocyclic rings given compound with high activity. Our analysis shows that there is a strong correlation between the structure of the compound and a substituent of the target molecule.