Biomaterials in Chimeric Antigen Receptor T-Cell Process Development

ConspectusChimeric antigen receptor (CAR) T-cell therapy has changed the landscape of cancer treatments, utilizing modified ex vivo autologous T cells to treat relapsed or refractory B-cell leukemia and lymphoma. However, the impact of wider therapy has been limited, in part, the production process is complicated, lengthy, and expensive. Thus, as a T-cell therapy CAR more developed to treat other cancers, continuous innovation in manufacturing cell will be crucial to their successful clinical implementation. This account, we describe our research efforts using biomaterials to raise three fundamental steps in T-cell manufacturing CAR: (1) isolation, (2) activation, and (3) genetic modification.Recognizing T cell isolation reagent clinically and supply costs a high obstacle, we developed a synthetic DNA aptamer and complementary reversal agent technology that CD8 + T cells isolated label-free with high purity and yield of mononuclear cells of peripheral blood.

Spirit, CAR T cells are made of both antibody and T cell-isolated aptamer comparable in therapeutic potential. Invention and design of other T-cell specific aptamers and corresponding reversal reagents can fully realize the potential of this approach, enabling inexpensive isolation of different T cell populations in a single insulating step.Current some material ex vivo T-cell activation does not accurately mimic the in situ activation of cells T by antigen presenting cells (APC). They are not the same cause expansion of CD4 + and CD8 + T cells, so it requires a separate production of CD4 + and CD8 + CAR T cells for therapeutic infusion calls for balanced composition.

To address this shortcoming, we designed a panel of cell-templated silica microparticles with a biodegradable supported lipid bilayers that display ligand stimulation of T-cell activation. high fluidity of the membrane, elongated shape, and rugged topography of the surface, all of the properties of endogenous APC, which was found to be a favorable parameter for activation, promote unbiased and efficient CD4 / CD8 T-cell expansion while not severe distinguish cells.Viral and electroporation-based delivery system gene has many weaknesses. viral vectors are expensive and limited the size of the cargo, while the highly cytotoxic electroporation.

Thus, low-cost platform nonviral that transfect T cells with low cytotoxicity and high efficiency required for CAR gene delivery. Our group thus synthesized cationic polymer panels with different architectures and evaluated their abilities T cell transfection. We identified a comb-shaped polymer formulations were transfected primary T cells with low cytotoxicity, although it was a low transfection efficiency compared to conventional methods.

 Biomaterials in Chimeric Antigen Receptor T-Cell Process Development
Biomaterials in Chimeric Antigen Receptor T-Cell Process Development

Analysis of intracellular and extracellular barriers to transfection reveal polyplexes low absorption and high endosomal pH in T cells, offensive biological properties and polymers that can further innovation improved.These represent only a few recent developments in the field of biomaterials to address the needs of CAR T cell production. Together, these technologies and their future progress would pave the way for the manufacture of T-cell CAR economical and easy.

CA 72-4 protein

30-AC23 50 KU
EUR 314.00
Description: Purified native Human CA 72-4 protein

CA 72-4 protein

30-AC24 50 KU
EUR 390.00
Description: Purified native Human CA 72-4 protein

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

DL-CA72-4-Hu-192 1 kit of 192 tests
EUR 1054.00
Description: An ELISA kit based on the sandwich method for detection and quantification of Human Carbohydrate Antigen 72-4 (CA72-4)

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

DL-CA72-4-Hu-48 1 kit of 48 tests
EUR 447.00
Description: An ELISA kit based on the sandwich method for detection and quantification of Human Carbohydrate Antigen 72-4 (CA72-4)

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

DL-CA72-4-Hu-96 1 kit of 96 tests
EUR 597.00
Description: An ELISA kit based on the sandwich method for detection and quantification of Human Carbohydrate Antigen 72-4 (CA72-4)

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

DLR-CA72-4-Hu-48T 48T
EUR 479.00
  • Should the Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 72-4 (CA72-4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

DLR-CA72-4-Hu-96T 96T
EUR 621.00
  • Should the Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 72-4 (CA72-4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

RD-CA72-4-Hu-48Tests 48 Tests
EUR 478.00

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

RD-CA72-4-Hu-96Tests 96 Tests
EUR 662.00

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

RDR-CA72-4-Hu-48Tests 48 Tests
EUR 500.00

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

RDR-CA72-4-Hu-96Tests 96 Tests
EUR 692.00

Human Cancer Antigen CA72-4 (TAG-72) Protein

abx061471-50kU 50 kU
EUR 1358.00
  • Shipped within 5-10 working days.

TM-CA 72-4 ELISA Kit

DEIA2148 96T
EUR 842.00
Description: The TM-CA 72-4 ELISA is an enzyme immunoassay for measurement of CA 72-4 ( TAG-72 ) in serum and plasma.

Carbohydrate Antigen 72-4 (CA72-4) Antibody

abx023799-1mg 1 mg
EUR 1156.00
  • Shipped within 5-10 working days.

Carbohydrate Antigen 72-4 (CA72-4) Antibody

abx023800-1mg 1 mg
EUR 1156.00
  • Shipped within 5-10 working days.

Carbohydrate Antigen 72-4 (CA72-4) Antibody

abx023801-1mg 1 mg
EUR 1156.00
  • Shipped within 5-10 working days.

Carbohydrate Antigen 72-4 (CA72-4) Antibody

20-abx102717
  • EUR 398.00
  • EUR 133.00
  • EUR 1107.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

CA 72-4, Human Metastatic Liver Carcinoma

P1436-1
EUR 164.00

CA 72-4, Human Metastatic Liver Carcinoma

P1436-5
EUR 642.00

TA(Anti-Trophoblast Membrane Antibody IgM) ELISA test

72 96T/Box Ask for price
  • Area of application: Immunological infertility
Description: ELISA based test for quantitative detection of TA(Anti-Trophoblast Membrane Antibody IgM)

Carbohydrate Antigen 72-4 (CA72-4) Antibody (Biotin)

20-abx272556
  • EUR 425.00
  • EUR 230.00
  • EUR 1191.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

ExoStd? Lyophilized Exosome Standard (30 µg, Human Plasma, 4 vials)

M1040-4
EUR 909.00

ExoStd? Lyophilized Exosome Standard (100 µg, Human Plasma, 4 vials)

M1041-4
EUR 1137.00

ExoStd? Lyophilized Exosome Standard (30 µg, Human Serum, 4 vials)

M1042-4
EUR 909.00

ExoStd? Lyophilized Exosome Standard (100 µg, Human Serum, 4 vials)

M1043-4
EUR 1132.00

ExoStd? Lyophilized Exosome Standard (30 µg, Human Urine, 4 vials)

M1044-4
EUR 909.00

ExoStd? Lyophilized Exosome Standard (100 µg, Human Urine, 4 vials)

M1045-4
EUR 1137.00

ExoStd? Lyophilized Exosome Standard (30 µg, Human Saliva, 4 vials)

M1046-4
EUR 914.00

ExoStd? Lyophilized Exosome Standard (100 µg, Human Saliva, 4 vials)

M1047-4
EUR 1137.00

ExoStd? Lyophilized Exosome Standard (30 µg, U87 MG, 4 vials)

M1054-4
EUR 914.00

ExoStd? Lyophilized Exosome Standard (100 µg, U87 MG, 4 vials)

M1055-4
EUR 1142.00

Recombinant Human HCC-1 (CCL14) (72 a.a.) Protein

PROTQ16627-4 10ug
EUR 317.00
Description: HCC-1 is a CC chemokine that signals through the CCR1 receptor and chemoattracts blood monocytes. It is secreted by various tissues including skeletal muscle, heart, spleen, liver and bone marrow. Recombinant human HCC-1 is an 8.4 kDa protein consisting of 72 amino acids including the four highly conserved residues present in CC chemokines.

Recombinant Human IL-8 (72 a.a.) (CXCL8) Protein

PROTP10145-4 25ug
EUR 317.00
Description: IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant human IL-8 (monocyte-derived) is an 8.4 kDa protein containing 72 amino acid residues.

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

abx572074-96tests 96 tests
EUR 786.00
  • Shipped within 5-12 working days.

Human carbonhydrate antigen 72-4 (CA72-4) ELISA kit

CSB-E09411h-24T 1 plate of 24 wells
EUR 165.00
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human carbonhydrate antigen 72-4 (CA72-4) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human carbonhydrate antigen 72-4 (CA72-4) ELISA kit

1-CSB-E09411h
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human carbonhydrate antigen 72-4 (CA72-4) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

ExoStd? Lyophilized Exosome Standard (30 µg, COLO1 cell line, 4 vials)

M1048-4
EUR 914.00

ExoStd? Lyophilized Exosome Standard (100 µg, COLO1 cell line, 4 vials)

M1049-4
EUR 1142.00

ExoStd? Lyophilized Exosome Standard (30 µg, MM1 cell line, 4 vials)

M1050-4
EUR 914.00

ExoStd? Lyophilized Exosome Standard (100 µg, MM1 cell line, 4 vials)

M1051-4
EUR 1142.00

ExoStd? Lyophilized Exosome Standard (30 µg, BLCL21 cell line, 4 vials)

M1052-4
EUR 914.00

ExoStd? Lyophilized Exosome Standard (100 µg, BLCL21 cell line, 4 vials)

M1053-4
EUR 1142.00

ExoStd? Lyophilized Exosome Standard (30 µg, HCT116 cell line, 4 vials)

M1058-4
EUR 914.00

ExoStd? Lyophilized Exosome Standard (100 µg, HCT116 cell line, 4 vials)

M1059-4
EUR 1142.00

ExoStd? Lyophilized Exosome Standard (30 µg, PC3 cell line, 4 vials)

M1060-4
EUR 914.00

ExoStd? Lyophilized Exosome Standard (100 µg, PC3 cell line, 4 vials)

M1061-4
EUR 1142.00

ExoStd? Lyophilized Exosome Standard (30 µg, DAUD1 cell line, 4 vials)

M1064-4
EUR 914.00

ExoStd? Lyophilized Exosome Standard (100 µg, DAUD1 cell line, 4 vials)

M1065-4
EUR 1142.00

ExoStd? Lyophilized Exosome Standard (30 µg, A549 cell line, 4 vials)

M1066-4
EUR 914.00

ExoStd? Lyophilized Exosome Standard (100 µg, A549 cell line, 4 vials)

M1067-4
EUR 1142.00

ExoStd? Lyophilized Exosome Standard (30 µg, B16F10 cell line, 4 vials)

M1070-4
EUR 914.00

ExoStd? Lyophilized Exosome Standard (100 µg, B16F10 cell line, 4 vials)

M1071-4
EUR 1142.00

Gastrointestinal Cancer Antigen (CA 19-9), antigen grade

CA1991-N-10 10 KU
EUR 529.00

ExoStd? Lyophilized Exosome Standard (30 µg, BPH-1 cell line, 4 vials)

M1062-4
EUR 914.00

ExoStd? Lyophilized Exosome Standard (100 µg, BPH-1 cell line, 4 vials)

M1063-4
EUR 1142.00

ExoStd? Lyophilized Exosome Standard (30 µg, K-562 cell line, 4 vials)

M1068-4
EUR 914.00

ExoStd? Lyophilized Exosome Standard (100 µg, K-562 cell line, 4 vials)

M1069-4
EUR 1142.00

ExoStd? Lyophilized Exosome Standard (30 µg, SK-N-SH cell line, 4 vials)

M1056-4
EUR 914.00

ExoStd? Lyophilized Exosome Standard (100 µg, SK-N-SH cell line, 4 vials)

M1057-4
EUR 1142.00

IL-4 Interleukin 4 Human Recombinant Protein, Yeast

PROTP05112-4 Regular: 10ug
EUR 317.00
Description: Interleukin-4 Human Recombinant produced in yeast is a single, glycosylated polypeptide chain containing 129 amino acids.;The IL-4 is purified by proprietary chromatographic techniques.

Lyophilized recombinant standard

ST0000-4 4ng/vial
EUR 172.00

Individual Reaction Mix 4

G065-4 200 reactions
EUR 167.00

Polystyrene Particle Size Standard

PPS-4 mL
EUR 131.00
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Inactivated RuV Grade 4 Antigen

VAng-Lsx0477-1mg 1 mg
EUR 3080.00
Description: RuV Grade 4, natural antigen.

pLenti-CLDN1 shRNA-4 Plasmid

PVTBAV04867-4 2 ug
EUR 356.00

Feline IL-4 Recombinant Protein

R00230-4 5ug/vial
EUR 259.00
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Feline IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.

DIGITAL SHAKER FOR 4 MICROPLATES, 120V

6780-4 1/pk
EUR 798.00
Description: Lab Equipment; Shakers & Mixers

Mouse FibrOut 4, for brain, neural

4-20507 1 ml Ask for price

Mouse FibrOut 4, for brain, neural

4-20508 5 x 1 ml Ask for price

Rat FibrOut 4, for brain, neural

4-20533 1 ml Ask for price

Rat FibrOut 4, for brain, neural

4-20534 5 x 1 ml Ask for price

Human FibrOut 4, for brain, neural

4-21552 1 ml Ask for price

Human FibrOut 4, for brain, neural

4-21553 5 x 1 ml Ask for price

Recombinant Human PF-4 (CXCL4) Protein

PROTP02776-4 20ug
EUR 317.00
Description: PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.

Recombinant Human 4-1BB Receptor Protein

PROTQ07011-4 20ug
EUR 317.00
Description: 4-1BB Receptor, a member of the TNF superfamily of receptors, is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB Receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain. Recombinant human soluble 4-1BB Receptor is a 167 amino acid polypeptide (17.7 kDa), which contains the cysteine rich TNFR-like extracellular domain of 4-1BB Receptor.

anti-Fc? RI? (human IgE receptor) antibody, monoclonal (CRA1)

72-001 100ug
EUR 414.00
Description: The anti-Fc? RI? (human IgE receptor) antibody, monoclonal (CRA1) is available in Europe and for worldwide shipping via Gentaur.

Biotinylated anti-Fc? RI? ?human IgE receptor) antibody (CRA1)

72-003 50ug
EUR 414.00
Description: The Biotinylated anti-Fc? RI? ?human IgE receptor) antibody (CRA1) is available in Europe and for worldwide shipping via Gentaur.

FITC-labeled anti-Fc? RI? ?human IgE receptor) antibody (CRA1)

72-004 50ug Ask for price
Description: The FITC-labeled anti-Fc? RI? ?human IgE receptor) antibody (CRA1) is available in Europe and for worldwide shipping via Gentaur.

anti-Fc? RI? ?human IgE receptor) antibody, monoclonal (CRA2)

72-005 100ug Ask for price
Description: The anti-Fc? RI? ?human IgE receptor) antibody, monoclonal (CRA2) is available in Europe and for worldwide shipping via Gentaur.

Biotinylated anti-Fc? RI? ?human IgE receptor) antibody (CRA2)

72-007 50ug
EUR 401.00
Description: The Biotinylated anti-Fc? RI? ?human IgE receptor) antibody (CRA2) is available in Europe and for worldwide shipping via Gentaur.

FITC-labeled anti-Fc? RI? ?human IgE receptor) antibody (CRA2)

72-008 50ug
EUR 401.00
Description: The FITC-labeled anti-Fc? RI? ?human IgE receptor) antibody (CRA2) is available in Europe and for worldwide shipping via Gentaur.

Bone Dissociation System 4 (Osteoblasts), Adult Mouse

4-20214 ea Ask for price

Liver Dissociation System 4 (Hepatocytes, rat), Rat

4-20304 ea Ask for price

Pituitary Dissociation System 4 (Pituitary), Adult mouse

4-20404 ea Ask for price

Thymus Dissociation System 4 (Epithelial), Adult rat

4-20444 ea Ask for price

Exo-Check Exosome Antibody Array (Neuro) Standard

EXORAY500A-4 4 arrays
EUR 690.00

DIGITAL SHAKER FOR 4 MICROPLATES, 230V-UK PLUG

6782-4 1/pk
EUR 798.00
Description: Lab Equipment; Shakers & Mixers

DIGITAL SHAKER FOR 4 MICROPLATES, 230V-EU PLUG

6781-4 1/pk
EUR 798.00
Description: Lab Equipment; Shakers & Mixers

Cartilage Dissociation System 4 (Chondrocytes), Mouse and Rat

4-20234 ea Ask for price

Mammary Dissociation System 4 (Epithelial, Swiss 3T3), Mouse

4-20324 ea Ask for price

Pancreas Dissociation System 4 (Islets), Mouse and Rat

4-20374 ea Ask for price

Skin Dissociation System 4 (Keratinocytes), Mouse and Rat

4-20434 ea Ask for price

Ovarian Cancer Antigen (CA 125)

CA1251-N-10 10 KU
EUR 529.00

Adipose/Fat Dissociation System 4 (Predipocytes), Mouse and Rat

4-20194 ea Ask for price

Brain Dissociation System 4 (Endothelial, Microvessels), Mouse and Rat

4-20224 ea Ask for price

Endothelial Dissociation System 4 (Endothelial,Cerebral), Mouse and Rat

4-20244 ea Ask for price

Heart Dissociation System 4 (Myocytes,Ventricles), Mouse and Rat

4-20274 ea Ask for price

Muscle Dissociation System 4 (Smooth muscle), Mouse and Rat

4-20334 ea Ask for price

Parotid Dissociation System 4 (Parotid acinar), Mouse and Rat

4-20394 ea Ask for price

Human Cancer OptiTDS1: Tissue Dissociation System

4-28024 1 Kit Ask for price

Human Cancer OptiTDS2: Tissue Dissociation System

4-28025 1 Kit Ask for price

Human Cancer OptiTDS3: Tissue Dissociation System

4-28026 1 Kit Ask for price

Human Cancer OptiTDS4: Tissue Dissociation System

4-28027 1 Kit Ask for price

Human Cancer OptiTDS5: Tissue Dissociation System

4-28028 1 Kit Ask for price

Human Cancer OptiTDS6: Tissue Dissociation System

4-28029 1 Kit Ask for price

Human Cancer OptiTDS7: Tissue Dissociation System

4-28030 1 Kit Ask for price

Human Cancer OptiTDS8: Tissue Dissociation System

4-28031 1 Kit Ask for price

Human Cancer OptiTDS9: Tissue Dissociation System

4-28032 1 Kit Ask for price

Human Cancer OptiTDS10: Tissue Dissociation System

4-28033 1 Kit Ask for price

Human Cancer OptiTDS11: Tissue Dissociation System

4-28034 1 Kit Ask for price

Human Cancer OptiTDS12: Tissue Dissociation System

4-28035 1 Kit Ask for price

Human Cancer OptiTDS13: Tissue Dissociation System

4-28036 1 Kit Ask for price

Human Cancer OptiTDS14: Tissue Dissociation System

4-28037 1 Kit Ask for price

Human Cancer OptiTDS15: Tissue Dissociation System

4-28038 1 Kit Ask for price

Human Cancer OptiTDS16: Tissue Dissociation System

4-28039 1 Kit Ask for price

Human Cancer OptiTDS18: Tissue Dissociation System

4-28041 1 Kit Ask for price

Human Cancer OptiTDS19: Tissue Dissociation System

4-28042 1 Kit Ask for price

Epithelial Dissociation System 4 (Epithelial,Submandibular salivary), Mouse and Rat

4-20254 ea Ask for price

Heart Dissociation System 4 (Retinal pigment epithelial), Mouse and Rat

4-20294 ea Ask for price

Lung Dissociation System 4 (Alveolar type II), Mouse and Rat

4-20314 ea Ask for price

Reproductive Tissue Dissociation System 4 (Epithelial, vagina), Mouse and Rat

4-20414 ea Ask for price

Cancer Antigen CA-125 Antigen (Human Fluids)

VAng-Wyb8639-inquire inquire Ask for price
Description: CA-125, Calibrator Grade, cancer antigen from Human Fluids, 53.26 KU/mL.

Cancer Antigen CA-125 Antigen (Human Adenocarcinoma)

VAng-Wyb8642-inquire inquire Ask for price
Description: CA-125, Calibrator Grade, Cancer antigen from Human Adenocarcinoma, 500 kIU / mL.

Adrenal Dissociation System 4 (Heart, Adrenal chromaffin, Paraneurons), Mouse and Rat

4-20204 ea Ask for price

Kidney Dissociation System 4 (Inner medullary duct,Papillae), Mouse and Rat

4-29294 ea Ask for price

TAG-72 (Tumor-Associated Glycoprotein 72)

MO47008 100 ul
EUR 349.00

Paraffin Tissue Section - Human Bone Tumor: Chondrosarcoma, Grade I - II

T2235023-4 5 slides
EUR 257.00
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Tumor Dissociation System 4 (Epithelial tumor,Neoplastic, Tumor, islet), Mouse and Rat

4-20484 ea Ask for price

BSA (Standard Grade)

30-AB70 1 kg
EUR 899.00
Description: Standard Grade Bovine Serum Albumin (99% pure)

Cancer Antigen CA 19-9 Antibody

abx023798-1mg 1 mg
EUR 878.00
  • Shipped within 5-10 working days.

Bovine Heat Shock Protein 72(HSP-72)

QY-E60086 96T
EUR 426.00

Human CCSA-4(Colon Cancer Specific Antigen-4) ELISA Kit

E-EL-H0795-192 192 tests
EUR 895.00
  • No significant cross-reactivity with analogues from other species was determined. Please, note that the data on cross-reactivity is limited. Other samples, aside from the tested ones, may be suitable to be used with this kit.
Description: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human CCSA-4. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human CCSA-4 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human CCSA-4, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Human CCSA-4. You can calculate the concentration of Human CCSA-4 in the samples by comparing the OD of the samples to the standard curve.

Human CCSA-4(Colon Cancer Specific Antigen-4) ELISA Kit

E-EL-H0795-96 96 tests
EUR 530.00
  • No significant cross-reactivity with analogues from other species was determined. Please, note that the data on cross-reactivity is limited. Other samples, aside from the tested ones, may be suitable to be used with this kit.
Description: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human CCSA-4. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human CCSA-4 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human CCSA-4, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Human CCSA-4. You can calculate the concentration of Human CCSA-4 in the samples by comparing the OD of the samples to the standard curve.

Monkey Colon Cancer Specific Antigen-4 (CCSA-4) ELISA Kit

abx358784-96tests 96 tests
EUR 825.00
  • Shipped within 5-12 working days.

Pig Colon Cancer Specific Antigen-4 (CCSA-4) ELISA Kit

abx360753-96tests 96 tests
EUR 825.00
  • Shipped within 5-12 working days.

Human Colon Cancer Specific Antigen 4 (CCSA-4) ELISA Kit

abx354340-96tests 96 tests
EUR 707.00
  • Shipped within 5-12 working days.

Chicken Colon Cancer Specific Antigen-4 (CCSA-4) ELISA Kit

abx355731-96tests 96 tests
EUR 825.00
  • Shipped within 5-12 working days.

Rabbit Colon Cancer Specific Antigen-4 (CCSA-4) ELISA Kit

abx363654-96tests 96 tests
EUR 825.00
  • Shipped within 5-12 working days.

Human colon cancer-specific antigen-4,CCSA-4 ELISA kit

201-12-1665 96 tests
EUR 440.00
  • This colon cancer-specific antigen-4 ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human colon cancer-specific antigen-4(CCSA-4)ELISA Kit

GA-E1681HM-48T 48T
EUR 289.00

Human colon cancer-specific antigen-4(CCSA-4)ELISA Kit

GA-E1681HM-96T 96T
EUR 466.00

Human colon cancer-specific antigen-4(CCSA-4)ELISA Kit

QY-E03945 96T
EUR 361.00

Neural Dissociation System 4 (Cerebella neurons Dorsa horn neurons Neurons, sympathetic Precursor Spinal), Mouse and Rat

4-20354 ea Ask for price

Inactivated RuV Grade 4 Antigen (Strain HPV-77)

VAng-0638Lsx-inquire inquire Ask for price
Description: RuV (Strain HPV-77) Grade 4 antigen, inactivated by UV and verified by infectivity testing. 0.50 mg/mL.

Tumor Dissociation System 3 (Epithelial cancer and tumor, Mammary tumors), Mouse and Rat

4-20483 ea Ask for price

MCA [7-Methoxycoumarin-4-acetic acid] *CAS 62935-72-2*

557 1 g
EUR 219.00
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

Cancer Antigen CA-125 Antigen (Human Fluids) (Partially Pure)

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Description: CA-125 (Ovarian Cancer), Partially Pure, Cancer antigen from Human Fluids, 73.90 kUnits/mL.

In this study, we assigned each 3 clinical plasma samples into 6 aliquots to assess five EV commercial isolation kit, compared with ultracentrifugation (UC). We apply the standard EV preparation and transcriptome analysis workflow except EV isolation methods are used. Metrics EVs and RNA cargo (evRNA) compared to assess the technical variation versus biological variation in the clinical setting.